Jynarque

Generic name: tolvaptan

Used for: Slowing kidney decline in polycystic kidney disease (ADPKD)

How do you pay?

How to pay the least

From

$165.50 for 30 tablets delivered ($160.25 plus $5.25 shipping)

Generic tolvaptan from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic tolvaptan. It comes by mail.

A regular generic has the same active ingredient as Jynarque, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameJynarque
Authorized generictolvaptan
Regular generictolvaptan
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Not soldThere isn’t one
From$165.50for 30 tablets at Cost Plus Drugs, with shipping
Same as Jynarque?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

JYNARQUE Commercial Copay Savings Program

Savings card from Otsuka America Pharmaceutical

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a month

The card takes up to $10,600 a year off your co-pay.

Sign up on jynarque.com 

Or call 1-855-242-7787.

In the maker’s words

“Eligible patients who have an activated Member Number under the Commercial Copay Savings Program, together with a valid prescription for JYNARQUE, may pay as little as $0 per 28-day supply of JYNARQUE.”

From the maker’s offer on jynarque.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Jynarque itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic tolvaptan, lowest first.

Delivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

3 companies sell a generic of Jynarque that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.

  • ApotexKit
    Packages and NDCs

    PackageNDC
    Carton of 460505-4800-0

    PackageNDC
    Carton of 460505-4801-0

    PackageNDC
    Carton of 460505-4802-0

    PackageNDC
    Carton of 460505-4803-0

    PackageNDC
    Carton of 460505-4804-0
  • Lupin PharmaceuticalsTablet 15 mg, 30 mg · Kit

    Has lactose

    How it looks, what’s in it, NDCs

    15 mg Pink, capsule, 7 mm, marked “F05 / LU”

    PackageNDC
    Bottle of 3070748-238-06

    30 mg Pink, round, 7 mm, marked “F06 / LU”

    PackageNDC
    Bottle of 3070748-239-06

    PackageNDC
    Carton of 470748-240-13

    PackageNDC
    Carton of 470748-241-13

    PackageNDC
    Carton of 470748-242-13

    PackageNDC
    Carton of 470748-243-13

    PackageNDC
    Carton of 470748-244-13

    Inactive ingredients: ferric oxide red, hydroxypropyl cellulose, low substituted, hydroxypropyl cellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, microcrystalline cellulose 302, starch, corn

    FDA label

  • Teva PharmaceuticalsKit

    Has lactose

    How it looks, what’s in it, NDCs

    PackageNDC
    Carton of 40480-3311-66

    PackageNDC
    Carton of 40480-3312-66

    PackageNDC
    Carton of 40480-3313-66

    PackageNDC
    Carton of 40480-3314-66

    PackageNDC
    Carton of 40480-3414-66

    Inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose 102, povidone k30, sodium lauryl sulfate

    FDA label

The FDA doesn’t rate Ascend Laboratories, Camber Pharmaceuticals, NorthStar Rx, Novadoz Pharmaceuticals and Par Health’s versions of tolvaptan a substitute for Jynarque, so a pharmacy can’t swap them in without your prescriber’s OK.

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Jynarque, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

JYNARQUE is a selective vasopressin V2-receptor antagonist indicated to slow kidney function decline in adults at risk of rapidly progressing autosomal dominant polycystic kidney disease (ADPKD)

Source: the FDA label for Jynarque (Otsuka America Pharmaceutical, Inc.), September 30, 2026. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/jynarque/