Brand-name prescription

Krystexxa

pegloticase

Compare your options

Krystexxa is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

Compare	KrystexxaBrand name	Authorized genericWithout the Krystexxa name	Regular genericpegloticase
What pharmacies pay	Price not listed	Not sold	Not sold
Same as Krystexxa?	The original	–	–
Ways to save	Maker’s cardas little as $0 an infusionwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: Krystexxa is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Amgen

Amgen Commercial Co-Pay Program (Amgen By Your Side)

With commercial insurance

as little as $0 an infusion

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

Get it on amgenbyyourside.com

In the maker’s words

“Eligible commercially insured patients may pay as little as $0 out-of-pocket for KRYSTEXXA and infusion costs through the Amgen Commercial Co-Pay Program.”

From the maker’s offer on amgenbyyourside.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Good to know

There’s no authorized generic of Krystexxa.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to the clinic’s billing office.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.