Krystexxa savings card: as little as $0 an infusion with commercial insurance

Krystexxa is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How to pay the least

Given by your care team

Billed by the clinic

Krystexxa is given by a doctor or nurse, not picked up at a pharmacy.

Ask your care team or your plan what you’d pay before your visit.

Compare every option

Brand nameKrystexxa

Authorized genericpegloticase

Regular genericpegloticase

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldAsk the pharmacy

Same as Krystexxa?

The original

–

Brand nameThe maker’s card

Amgen Commercial Co-Pay Program (Amgen By Your Side)

Savings card from Amgen

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 an infusion

See the offer on amgenbyyourside.com

In the maker’s words

“Eligible commercially insured patients may pay as little as $0 out-of-pocket for KRYSTEXXA and infusion costs through the Amgen Commercial Co-Pay Program.”

From the maker’s offer on amgenbyyourside.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Krystexxa itself, from the same company, sold without the brand name, and usually for less. For now Krystexxa is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Krystexxa is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Chronic gout not helped by usual treatments

What the FDA label says

KRYSTEXXA® (pegloticase) is a PEGylated uric acid specific enzyme indicated for the treatment of chronic gout in adult patients refractory to conventional therapy.

Limitations of Use: KRYSTEXXA is not recommended for the treatment of asymptomatic hyperuricemia.

Source: the FDA label for Krystexxa (Horizon Therapeutics USA, Inc.), July 9, 2026. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to the clinic’s billing office.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/krystexxa/