How to pay the least
Lowest price
$298.33 for 30 tablets delivered ($293.08 plus $5.25 shipping)
Generic sapropterin dihydrochloride 100 mg from Cost Plus Drugs, by mail
- Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs
- Order generic sapropterin dihydrochloride 100 mg. It comes by mail.
Need it today? $337.90 for 30 tablets with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.
See the price and get the cardA regular generic has the same active ingredient as Kuvan, and the FDA requires it to work the same way.
Compare every option
Details for each option
Brand nameNo maker’s card
We didn’t find a savings card or cash price from Kuvan’s maker. Ask the pharmacy for Kuvan’s cash price. With insurance, ask what your plan charges.
Authorized genericNot sold
There isn’t one. An authorized generic is Kuvan itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.
Regular genericWhere to buy it
Pharmacies’ own cash prices for generic sapropterin dihydrochloride, lowest first.
Pick up in storeDelivered
- Delivered: Cost Plus Drugs $293.08for 30 tablets100 mgPlus $5.25 shipping
- Pick up in store: Team Cuban Card $337.90for 30 tablets100 mgFree card · Kroger, Albertsons, Safeway, Meijer and many local pharmaciesFind a pharmacy that takes it
- Delivered: Amazon Pharmacy $967.70for 30 tablets100 mgPrime members only · $139 a year · Free delivery · Prime price: limits on some medicines if you're over 65 or have Medicare, Medicaid or TRICARE
From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.
About these prices
Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.
Regular genericMakers and their savings cards
8 companies sell a generic of Kuvan that the FDA rates a substitute. A pharmacy fills whichever one it stocks. 2 of them have their own savings cards or programs, listed first. Each works only with that maker’s version. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.
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Dr. Reddy’s LaboratoriesTablet 100 mg · Powder 100 mg, 500 mg
Sold as Javygtor
Cycle Vita Co-Pay Assistance Program
With commercial insurance as little as $0
Ask for Javygtor by name, or have your prescriber write it on the prescription.
In the maker’s words
“With JAVYGTOR, commercially insured eligible patients may pay as little as $0.”
Cycle Vita Co-Pay Assistance Program (JAVYGTOR sapropterin)
With commercial insurance as little as $0
See the offer on cyclevita.life
In the maker’s words
“Commercially insured eligible patients may pay as little as $0.”
How it looks, what’s in it, NDCs
100 mg Off white to light yellow, round, 9 mm, marked “l”
Package NDC Bottle of 30 43598-096-30 Bottle of 120 43598-096-04 Bottle of 500 43598-096-05 100 mg Off white to pale yellow
Package NDC Carton of 30 43598-097-30 500 mg Off white to pale yellow
Package NDC Carton of 30 43598-162-30 Inactive ingredients: ascorbic acid, silicon dioxide, crospovidone, hydroxypropyl cellulose, low substituted, mannitol, riboflavin, sodium stearyl fumarate, sucralose, potassium citrate
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Camber PharmaceuticalsTablet 100 mg · Powder 100 mg, 500 mg
Made by Annora Pharma
Camber Copay Assistance Program (Camber Pharmaceuticals Co-Pay Program)
“To help alleviate the burden some drug prices create, Camber has made a copayment assistance program to help offset rising drug prices.” (patients not covered by any federal or state healthcare program (Medicare, Medicaid, Medigap, VA/DOD, TRICARE excluded); page says 'All non-excluded patients are eligible')
Product page on camberpharma.com
How it looks, what’s in it, NDCs
100 mg Off-white to light yellow, round, 10 mm, marked “I1”
Package NDC Bottle of 120 31722-045-12 100 mg Off-white to yellow
Package NDC Carton of 1 31722-047-31 Carton of 30 31722-047-30 500 mg Off-white to yellow
Package NDC Carton of 1 31722-048-31 Carton of 30 31722-048-30 Inactive ingredients: ascorbic acid, silicon dioxide, crospovidone (120 .mu.m), mannitol, riboflavin, sodium stearyl fumarate, potassium citrate, sucralose
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Aurobindo PharmaTablet 100 mg
Product page on aurobindousa.com
How it looks, what’s in it, NDCs
100 mg Off-white to light yellow, round, 10 mm, marked “S1”
Package NDC Bottle of 30 59651-574-30 Bottle of 120 59651-574-08 Bottle of 240 59651-574-24 Inactive ingredients: ascorbic acid, crospovidone (120 .mu.m), anhydrous dibasic calcium phosphate, mannitol, riboflavin, sodium stearyl fumarate
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Hikma PharmaceuticalsTablet 100 mg
How it looks, what’s in it, NDCs
100 mg (off-white to light yellow), round, 10 mm, marked “ZS”
Package NDC Bottle of 120 0054-0906-23 Inactive ingredients: mannitol, anhydrous dibasic calcium phosphate, ascorbic acid, riboflavin, sodium stearyl fumarate, crospovidone (120 .mu.m)
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Micro LabsPowder 100 mg
Product page on microlabsusa.com
How it looks, what’s in it, NDCs
100 mg To off-white
Package NDC Carton of 30 42571-509-41 Inactive ingredients: ascorbic acid, mannitol, potassium citrate, sucralose
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NorthStar RxTablet 100 mg · Powder 100 mg, 500 mg
Made by Annora Pharma
Product page on northstarrxllc.com
How it looks, what’s in it, NDCs
100 mg Off-white to light yellow, round, 10 mm, marked “I1”
Package NDC Bottle of 120 72603-191-01 100 mg Off-white to yellow
Package NDC Carton of 30 72603-193-30 500 mg Off-white to yellow
Package NDC Carton of 30 72603-194-30 Inactive ingredients: ascorbic acid, silicon dioxide, crospovidone (120 .mu.m), mannitol, riboflavin, sodium stearyl fumarate, potassium citrate, sucralose
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Par HealthTablet 100 mg · Powder 100 mg, 500 mg
Made by PH Health
How it looks, what’s in it, NDCs
100 mg Off-white to light yellow, round, 10 mm, marked “P / 720”
Package NDC Bottle of 120 49884-720-08 100 mg Off-white to lightly yellow
Package NDC Carton of 30 49884-948-72 500 mg Off-white to lightly yellow
Package NDC Carton of 30 49884-873-72 Inactive ingredients: ascorbic acid, silicon dioxide, copovidone k25-31, crospovidone, anhydrous dibasic calcium phosphate, mannitol, riboflavin, sodium stearyl fumarate, potassium citrate, sucralose
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TruPharmaPowder 100 mg, 500 mg
Made by Hopewell Pharma Ventures
How it looks, what’s in it, NDCs
100 mg Off-white to pale yellow
Package NDC Pouch of 1 52817-850-01 Carton of 30 52817-850-30 500 mg Off-white to pale yellow
Package NDC Pouch of 1 52817-851-01 Carton of 30 52817-851-30 Inactive ingredients: ascorbic acid, mannitol, potassium citrate, sucralose
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
What to say at the pharmacy
“Before you fill my Kuvan, can you tell me what I’d pay for the brand and for a generic?”
Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.
What it’s used for
What the FDA label says
KUVAN is a phenylalanine hydroxylase activator indicated to reduce blood phenylalanine (Phe) levels in adult and pediatric patients one month of age and older with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin‑ (BH4‑) responsive Phenylketonuria (PKU). KUVAN is to be used in conjunction with a Phe‑restricted diet.
Source: the FDA label for Kuvan (BioMarin Pharmaceutical Inc.), August 26, 2024. Full label on DailyMed
Good to know
- A regular generic may look different from Kuvan. The FDA requires it to work the same way.
- We didn’t find a savings card from Kuvan’s maker.
- Don’t stop or change a medicine without talking to your pharmacist or prescriber.
Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/kuvan/