Letairis

Generic name: ambrisentan

Used for: High blood pressure in the lungs (PAH)

How do you pay?

How to pay the least

From

$83.10 for 30 tablets

Generic ambrisentan with the free Team Cuban Card, at pharmacies that take it. Pick the strength on your label above for its own price.

  1. Get the free Team Cuban Card. It costs nothing to sign up.See the price and get the card 
  2. At a pharmacy that takes it, show the card and ask for generic ambrisentan.Find a pharmacy that takes it 

A regular generic has the same active ingredient as Letairis, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameLetairis
Authorized genericambrisentan
Regular genericambrisentan
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Not soldThere isn’t one
From$83.10for 30 tablets at Team Cuban Card
Same as Letairis?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Letairis Co-Pay Coupon Program

Savings card from Gilead Sciences

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $5 a month

The card takes up to $20,000 a year off your co-pay.

Sign up on letairis.com 

Or call 1-866-664-5327.

In the maker’s words

“Patients who have commercial insurance may pay as little as $5 per month for Letairis.”

From the maker’s offer on letairis.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Letairis itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic ambrisentan, lowest first.

Pick up in store

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericMakers and their savings cards

7 companies sell a generic of Letairis that the FDA rates a substitute. A pharmacy fills whichever one it stocks. 3 of them have their own savings cards, listed first. Each works only with that maker’s version. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Actavis PharmaAll 2 strengths

    Has lactose · Made by Watson Laboratories

    Teva Generics copay savings card (Ambrisentan Tablets)

    With commercial insurance as little as $0 a prescription

    Print the card (PDF)

    Or call 1-844-248-7949. See the offer on tevausa.com

    In the maker’s words

    “Patients may pay as little as $0 out of pocket for Teva’s Ambrisentan Tablets.”

    How it looks, what’s in it, NDCs

    5 mg White to off-white, oval, 8 mm, marked “5 / 405”

    PackageNDC
    Bottle of 300591-2405-30

    10 mg White to off-white, oval, 11 mm, marked “10 / 406”

    PackageNDC
    Bottle of 300591-2406-30

    Inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, cellulose, microcrystalline, lecithin, soybean, polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • CiplaAll 2 strengths

    Has lactose · Has a dye: FD&C Red No. 40

    Cipla Universal Copay Program (ambrisentan)

    For ambrisentan tablets 5 mg, 10 mg

    With commercial insurance as little as $5 a month

    Sign up on usa.cipla.com

    Or call 1-877-331-7668.

    In the maker’s words

    “If you have private or commercial prescription insurance, you may be eligible to receive Ambrisentan tablets for as little as $5 per month, subject to monthly and annual limits.”

    How it looks, what’s in it, NDCs

    5 mg Pale, square, 7 mm, marked “C / 386”

    PackageNDC
    Carton of 1069097-386-19
    Bottle of 3069097-386-02

    10 mg Deep, oval, 10 mm, marked “C / 387”

    PackageNDC
    Carton of 1069097-387-19
    Bottle of 3069097-387-02

    Inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, cellulose, microcrystalline, FD&C Red No. 40, lecithin, soybean, polyethylene glycol 4000, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • Zydus LifesciencesAll 2 strengths

    Has lactose · Has a dye: FD&C Red No. 40

    Zydus Copay Savings Program

    With commercial insurance as little as $0

    Print the card (PDF)

    See the offer on zydususa.com

    In the maker’s words

    “Eligible patients who have commercial insurance, pay as little as $0 co-pay per prescription.”

    How it looks, what’s in it, NDCs

    5 mg PINK, round, 8 mm, marked “1179”

    PackageNDC
    Carton of 1070710-1179-7
    Bottle of 3070710-1179-3
    Carton of 3070710-1179-8
    Bottle of 9070710-1179-9
    Bottle of 10070710-1179-1

    10 mg OFF WHITE, oval, 10 mm, marked “1180”

    PackageNDC
    Carton of 1070710-1180-7
    Bottle of 3070710-1180-3
    Carton of 3070710-1180-8
    Bottle of 9070710-1180-9
    Bottle of 10070710-1180-1

    Inactive ingredients: croscarmellose sodium, lactose monohydrate, lecithin, soybean, magnesium stearate, cellulose, microcrystalline, polyethylene glycol, povidone, talc, titanium dioxide, FD&C Red No. 40, aluminum oxide, polyvinyl alcohol

    FDA label

  • ApotexAll 2 strengths

    Has lactose · Has dyes: FD&C Red No. 40, FD&C Yellow No. 6

    How it looks, what’s in it, NDCs

    5 mg Pale pink, square, 6 mm, marked “APO / A5”

    PackageNDC
    Bottle of 3060505-4552-3

    10 mg Deep pink, oval, 10 mm, marked “APO / A10”

    PackageNDC
    Bottle of 3060505-4553-3

    Inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, FD&C Red No. 40, aluminum oxide, FD&C Yellow No. 6, polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • Aurobindo PharmaAll 2 strengths

    Has lactose · Has a dye: FD&C Red No. 40

    Product page on aurobindousa.com

    How it looks, what’s in it, NDCs

    5 mg Pale pink, square, 7 mm, marked “AS / 5”

    PackageNDC
    Bottle of 3059651-494-30

    10 mg Deep pink, oval, 10 mm, marked “AS / 10”

    PackageNDC
    Bottle of 3059651-495-30

    Inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, FD&C Red No. 40, lecithin, soybean, polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • Mylan PharmaceuticalsAll 2 strengths

    Has lactose · Has dyes: FD&C Blue No. 2, FD&C Red No. 40

    Product page on viatris.com

    How it looks, what’s in it, NDCs

    5 mg Pink, round, 6 mm, marked “M / AN”

    PackageNDC
    Bottle of 300378-4270-93

    10 mg Pink, oval, 10 mm, marked “M / AN1”

    PackageNDC
    Bottle of 300378-4271-93

    Inactive ingredients: anhydrous lactose, croscarmellose sodium, FD&C Blue No. 2, FD&C Red No. 40, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • Sigmapharm LaboratoriesAll 2 strengths

    Has lactose · Has dyes: FD&C Blue No. 2, FD&C Red No. 40

    Product page on sigmapharm.com

    How it looks, what’s in it, NDCs

    5 mg Light pink, square, 7 mm, marked “51”

    PackageNDC
    Bottle of 1042794-051-22
    Bottle of 3042794-051-08

    10 mg Dark pink, oval, 10 mm, marked “52”

    PackageNDC
    Bottle of 1042794-052-22
    Bottle of 3042794-052-08

    Inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, cellulose, microcrystalline, FD&C Red No. 40, aluminum oxide, polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide, FD&C Blue No. 2

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

What to say at the pharmacy

“Before you fill my Letairis, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

Letairis is an endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1) in adult patients:

  • To improve exercise ability and delay clinical worsening.
  • In combination with tadalafil to reduce the risks of disease progression and hospitalization for worsening PAH, and to improve exercise ability.

Studies establishing effectiveness included trials predominantly in patients with WHO Functional Class II–III symptoms and etiologies of idiopathic or heritable PAH (60%) or PAH associated with connective tissue diseases (34%).

Source: the FDA label for Letairis (Gilead Sciences, Inc.), June 22, 2026. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/letairis/