Brand-name prescription

Lupron Depot

leuprolide

Compare your options

Compare	Lupron DepotBrand name	Authorized genericWithout the Lupron Depot name	Regular genericleuprolide
What pharmacies pay	from$1,822–6,516per kit	Not sold	Not sold
Same as Lupron Depot?	The original	–	–
Ways to save	Maker’s cardas little as $10 a dosewith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: No generic is sold yet.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card AbbVie

LUPRON DEPOT Co-pay Savings Card

With commercial insurance

as little as $10 a dose

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

The card pays up to $300 a month.

Get it on luprongyn.com

In the maker’s words

“The Lupron Depot Savings Card can help eligible, commercially insured patients pay as little as $10 for LUPRON DEPOT.”

From the maker’s offer on luprongyn.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Lupron Depot’s own card may bring it to as little as $10 a dose.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Lupron Depot
3.75 mg kitper kit	$1,822
11.25 mg 3mo kitper kit	$5,437
7.5 mg 1 month ktper kit	$2,174
22.5 mg 3mo kitper kit	$6,516

Good to know

There’s no authorized generic of Lupron Depot.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.