How do you pay?

How to pay the least

Cash price

$1,650+ for 30 tablets

Pharmacies pay about this for Lybalvi; you’d pay more.

  1. Ask your pharmacy for Lybalvi’s cash price, and one or two other pharmacies too.
  2. Lybalvi’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify LYBALVI Patient Assistance Program. I understand that to qualify for the Patient Assistance Program, my household income and household size must meet program requirements. Or call 1-844-592-2584.

See if you qualify 

No generic is sold yet.

Compare every option

Question
Brand nameLybalvi
Authorized genericolanzapine and samidorphan l-malate
Regular genericolanzapine and samidorphan l-malate
What you’d pay
At least$1,650for 30 tablets; pharmacies pay this
Not soldThere isn’t one
Not soldNone sold yet
Same as Lybalvi?
The original
–
–

Brand nameThe maker’s card

LYBALVI Co-pay Savings Program

Savings card from Alkermes

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $20 a month

The card takes up to $450 a month off your co-pay.

Sign up on lybalvi.com 

Or text COPAY to 45286, or call 1-800-657-7613.

In the maker’s words

“Beginning at the fourth prescription and thereafter, eligible patients may pay as little as $20 with a maximum co-pay savings of $450 per 30-day supply.”

From the maker’s offer on lybalvi.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Lybalvi itself, from the same company, sold without the brand name, and usually for less. For now Lybalvi is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

LYBALVI is a combination of olanzapine, an atypical antipsychotic, and samidorphan, an opioid antagonist, indicated for the treatment of:

  • Schizophrenia in adults
  • Bipolar I disorder in adults
    • Acute treatment of manic or mixed episodes as monotherapy and as adjunct to lithium or valproate
    • Maintenance monotherapy treatment

Source: the FDA label for Lybalvi (Alkermes, Inc.), January 31, 2026. Full label on DailyMed 

Good to know