An authorized generic of Macrodantin was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (macrocrystalline nitrofurantoin) is available.
Source: FDA, updated October 30, 2026
How to pay the least
Ask for the cash price
Generic macrocrystalline nitrofurantoin
No pharmacy we check posts a price for it.
- Ask your pharmacy for the cash price of generic macrocrystalline nitrofurantoin.Find pharmacies near you
- Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.
A regular generic has the same active ingredient as Macrodantin, and the FDA requires it to work the same way.
Compare every option
Question
Brand nameMacrodantin
Authorized genericmacrocrystalline nitrofurantoin
Regular genericmacrocrystalline nitrofurantoin
What you’d pay
Not soldNo longer sold
Not soldNo longer sold
Cash priceAsk the pharmacy
Same as Macrodantin?
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Same active ingredientFillers and dyes can differ
Details for each option
Details for
Brand nameNot sold
Macrodantin itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.
Authorized genericNot sold now
Regular genericWho makes it
7 companies sell a generic of Macrodantin that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
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Alembic Pharmaceuticals25 mg, 50 mg, 100 mg
Has lactose · Has dyes: D&C Red No. 33, D&C Yellow No. 10
How it looks, what’s in it, NDCs
25 mg White, capsule, 14 mm, marked “A219”
Package NDC Bottle of 100 62332-389-31 Bottle of 1000 62332-389-91 50 mg Yellow and white, capsule, 16 mm, marked “A220”
Package NDC Bottle of 100 62332-390-31 Bottle of 1000 62332-390-91 100 mg Yellow, capsule, 18 mm, marked “A221”
Package NDC Bottle of 100 62332-391-31 Bottle of 1000 62332-391-91 Inactive ingredients: lactose monohydrate, starch, corn, talc, gelatin, titanium dioxide, shellac, propylene glycol, potassium hydroxide, ferrosoferric oxide, D&C Red No. 33, D&C Yellow No. 10
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Amneal Pharmaceuticals50 mg, 100 mg
Has lactose · Has dyes: D&C Red No. 33, D&C Yellow No. 10, FD&C Blue No. 1, FD&C Blue No. 2, FD&C Red No. 40 · Made by Impax Laboratories
How it looks, what’s in it, NDCs
50 mg Pink and white, capsule, 16 mm, marked “Z / Zenith / 50mg / 2130”
Package NDC Bottle of 100 0115-1643-01 Bottle of 1000 0115-1643-03 100 mg Pink, capsule, 18 mm, marked “Z / Zenith / 100mg / 2131”
Package NDC Bottle of 100 0115-1645-01 Bottle of 1000 0115-1645-03 Inactive ingredients: starch, corn, ferrosoferric oxide, D&C Yellow No. 10, aluminum oxide, FD&C Blue No. 1, FD&C Blue No. 2, indigotindisulfonate sodium, FD&C Red No. 40, propylene glycol, shellac, gelatin, lactose monohydrate, talc, titanium dioxide, D&C Red No. 33
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Aurobindo Pharma50 mg, 100 mg
Has lactose
How it looks, what’s in it, NDCs
50 mg Light brown opaque, capsule, 18 mm, marked “NT50”
Package NDC Bottle of 100 59651-753-01 100 mg Gray opaque, capsule, 18 mm, marked “NT100”
Package NDC Bottle of 100 59651-795-01 Inactive ingredients: silicon dioxide, starch, corn, gelatin, lactose monohydrate, magnesium stearate, ferric oxide red, sodium lauryl sulfate, titanium dioxide, ferric oxide yellow, ferrosoferric oxide, potassium hydroxide, propylene glycol, shellac, talc
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BluePoint Laboratories25 mg, 50 mg, 100 mg
Has lactose · Has dyes: FD&C Blue No. 1, FD&C Red No. 3 · Made by Mankind Pharma
How it looks, what’s in it, NDCs
25 mg Opaque cap and body, capsule, 11 mm, marked “LS / 410”
Package NDC Bottle of 100 68001-603-00 50 mg Opaque cap and opaque body, capsule, 16 mm, marked “LS / 411”
Package NDC Bottle of 100 68001-604-00 100 mg Opaque cap and body, capsule, 18 mm, marked “LS / 412”
Package NDC Bottle of 100 68001-605-00 Inactive ingredients: starch, corn, talc, titanium dioxide, gelatin, shellac, ferrosoferric oxide, potassium hydroxide, lactose monohydrate, FD&C Red No. 3, FD&C Blue No. 1
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Lupin Pharmaceuticals50 mg, 100 mg
Has lactose · Made by Novel Laboratories
How it looks, what’s in it, NDCs
50 mg Pink, capsule, 16 mm, marked “50mg / Novel”
Package NDC Bottle of 100 43386-641-01 100 mg Gray, capsule, 18 mm, marked “100mg / Novel”
Package NDC Bottle of 100 43386-642-01 Inactive ingredients: lactose monohydrate, starch, corn, talc, ferric oxide red, ferric oxide yellow, shellac, potassium hydroxide, titanium dioxide, gelatin, ferrosoferric oxide, propylene glycol
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NorthStar Rx25 mg, 50 mg, 100 mg
Has lactose · Has dyes: FD&C Blue No. 1, FD&C Red No. 3 · Made by Mankind Pharma
How it looks, what’s in it, NDCs
25 mg Opaque cap and body, capsule, 11 mm, marked “LS / 410”
Package NDC Bottle of 100 72603-182-01 50 mg Opaque cap and opaque body, capsule, 16 mm, marked “LS / 411”
Package NDC Bottle of 100 72603-183-01 100 mg Opaque cap and body, capsule, 18 mm, marked “LS / 412”
Package NDC Bottle of 100 72603-184-01 Inactive ingredients: lactose monohydrate, starch, corn, talc, titanium dioxide, gelatin, shellac, ferrosoferric oxide, potassium hydroxide, FD&C Red No. 3, FD&C Blue No. 1
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Zydus Lifesciences50 mg
Has lactose · Has dyes: FD&C Blue No. 1, FD&C Red No. 3
How it looks, what’s in it, NDCs
50 mg Blue opaque and white opaque, capsule, 16 mm, marked “559”
Package NDC Bottle of 100 68382-559-01 Carton of 100 68382-559-30 Bottle of 1000 68382-559-10 Inactive ingredients: FD&C Blue No. 1, FD&C Red No. 3, gelatin, lactose monohydrate, magnesium stearate, sodium lauryl sulfate, starch, corn, talc, titanium dioxide
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What it’s used for
What the FDA label says
INDICATIONS AND USAGE:
Macrodantin is specifically indicated for the treatment of urinary tract infections when due to susceptible strains of Escherichia coli, enterococci, Staphylococcus aureus, and certain susceptible strains of Klebsiella and Enterobacter species.
Nitrofurantoin is not indicated for the treatment of pyelonephritis or perinephric abscesses.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Macrodantin and other antibacterial drugs, Macrodantin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Nitrofurantoins lack the broader tissue distribution of other therapeutic agents approved for urinary tract infections. Consequently, many patients who are treated with Macrodantin are predisposed to persistence or reappearance of bacteriuria. Urine specimens for culture and susceptibility testing should be obtained before and after completion of therapy. If persistence or reappearance of bacteriuria occurs after treatment with Macrodantin, other therapeutic agents with broader tissue distribution should be selected. In considering the use of Macrodantin, lower eradication rates should be balanced against the increased potential for systemic toxicity and for the development of antimicrobial resistance when agents with broader tissue distribution are utilized.
Source: the FDA label for Macrodantin (Procter & Gamble Pharmaceuticals), March 23, 2009. Full label on DailyMed
Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/macrodantin/