An authorized generic of Megace ES was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (megestrol acetate) is available.
Source: FDA, updated October 30, 2026
Generic name: megestrol
Used for: Loss of appetite and weight loss in AIDS
Ask for the cash price
Generic megestrol
No pharmacy we check posts a price for it.
A regular generic has the same active ingredient as Megace ES, and the FDA requires it to work the same way.
Details for each option
Megace ES itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.
An authorized generic of Megace ES was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (megestrol acetate) is available.
Source: FDA, updated October 30, 2026
Generic megestrol is sold. Ask the pharmacy for its cash price. With insurance, ask what your plan charges.
Megace ES is indicated for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS).
Limitations of Use Therapy with Megace ES for weight loss should only be instituted after treatable causes of weight loss are sought and addressed. These treatable causes include possible malignancies, systemic infections, gastrointestinal disorders affecting absorption, endocrine disease, renal disease or psychiatric diseases. Megace ES is not intended for prophylactic use to avoid weight loss.
Source: the FDA label for Megace ES (Endo Operations), December 18, 2018. Full label from the FDA (PDF)
Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/megace-es/