How do you pay?

How to pay the least

Ask for the cash price

Generic megestrol

No pharmacy we check posts a price for it.

  1. Ask your pharmacy for the cash price of generic megestrol.Find pharmacies near you 
  2. Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Megace ES, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameMegace ES
Authorized genericmegestrol
Regular genericmegestrol
What you’d pay
Not soldNo longer sold
Not soldNo longer sold
Cash priceAsk the pharmacy
Same as Megace ES?
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–
Same active ingredientFillers and dyes can differ

Brand nameNot sold

Megace ES itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

Authorized genericNot sold now

An authorized generic of Megace ES was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (megestrol acetate) is available.

Source: FDA, updated October 30, 2026

Regular genericAsk the pharmacy

Generic megestrol is sold. Ask the pharmacy for its cash price. With insurance, ask what your plan charges.

What it’s used for

What the FDA label says

Megace ES is indicated for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS).

Limitations of Use Therapy with Megace ES for weight loss should only be instituted after treatable causes of weight loss are sought and addressed. These treatable causes include possible malignancies, systemic infections, gastrointestinal disorders affecting absorption, endocrine disease, renal disease or psychiatric diseases. Megace ES is not intended for prophylactic use to avoid weight loss.

Source: the FDA label for Megace ES (Endo Operations), December 18, 2018. Full label from the FDA (PDF)