How do you pay?

How to pay the least

Ask for the cash price

Generic estradiol

No pharmacy we check posts a price for it.

  1. Ask your pharmacy for the cash price of generic estradiol.Find pharmacies near you 
  2. Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Menostar, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameMenostar
Authorized genericestradiol
Regular genericestradiol
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Not soldThere isn’t one
Cash priceAsk the pharmacyUsually the lowest
Same as Menostar?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Menostar’s maker. Ask the pharmacy for Menostar’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Menostar itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWho makes it

One company sells a generic of Menostar that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Mylan Pharmaceuticals0.025 mg/day, 0.0375 mg/day, 0.05 mg/day, 0.06 mg/day, 0.075 mg/day, 0.1 mg/day

    Product page on viatris.com

    How it looks, what’s in it, NDCs

    0.025 mg/day

    PackageNDC
    Carton of 280378-3349-99

    0.0375 mg/day

    PackageNDC
    Carton of 280378-3360-99

    0.05 mg/day

    PackageNDC
    Carton of 280378-3350-99

    0.06 mg/day

    PackageNDC
    Carton of 280378-3361-99

    0.075 mg/day

    PackageNDC
    Carton of 280378-3351-99

    0.1 mg/day

    PackageNDC
    Carton of 280378-3352-99

    Inactive ingredients: propylene glycol, povidone, silicon dioxide

    FDA label

The FDA doesn’t rate Amneal Pharmaceuticals’s version of estradiol a substitute for Menostar, so a pharmacy can’t swap it in without your prescriber’s OK.

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Menostar, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

Menostar is an estrogen indicated for:

  • Prevention of Postmenopausal Osteoporosis Limitations of Use When prescribing solely for the prevention of postmenopausal osteoporosis, first consider the use of non-estrogen medications. Consider estrogen therapy only for women at significant risk of osteoporosis.

Source: the FDA label for Menostar (Bayer HealthCare Pharmaceuticals Inc.), March 12, 2026. Full label on DailyMed 

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