How do you pay?

How to pay the least

Lowest price

$168.57 for 30 tablets delivered ($163.32 plus $5.25 shipping)

Generic phytonadione 5 mg from Cost Plus Drugs, by mail

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic phytonadione 5 mg. It comes by mail.

Need it today? $184.28 for 30 tablets with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card 

A regular generic has the same active ingredient as Mephyton, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameMephyton
Authorized genericphytonadione
Regular genericphytonadione
What you’d pay
Not soldNo longer sold
Not soldNo longer sold
Cash price$168.57for 30 tablets at Cost Plus Drugs, with shipping
Same as Mephyton?
–
–
Same active ingredientFillers and dyes can differ

Brand nameNot sold

Mephyton itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the regular generic →

Authorized genericNot sold now

An authorized generic of Mephyton was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (phytonadione) is available.

Source: FDA, updated October 30, 2026

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic phytonadione, lowest first.

Pick up in storeDelivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

6 companies sell a generic of Mephyton that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Amneal Pharmaceuticals5 mg

    Has lactose

    How it looks, what’s in it, NDCs

    5 mg Light yellow to yellow, round, 6 mm, marked “AA / 05”

    PackageNDC
    Carton of 3069238-1051-3
    Carton of 10069238-1051-1

    Inactive ingredients: acaciella angustissima bark, anhydrous dibasic calcium phosphate, lactose monohydrate, magnesium stearate, silicon dioxide, starch, corn, talc

    FDA label

  • Cipla5 mg

    Has lactose · Made by ScieGen Pharmaceuticals

    How it looks, what’s in it, NDCs

    5 mg Pale yellow, round, 6 mm, marked “SG / 333”

    PackageNDC
    Bottle of 3069097-999-02
    Bottle of 10069097-999-07

    Inactive ingredients: acacia, anhydrous dibasic calcium phosphate, lactose monohydrate, magnesium stearate, starch, corn, silicon dioxide, talc

    FDA label

  • Exelan Pharmaceuticals5 mg

    Has lactose · Made by ScieGen Pharmaceuticals

    How it looks, what’s in it, NDCs

    5 mg Pale yellow, round, 6 mm, marked “SG / 333”

    PackageNDC
    Carton of 3076282-740-30

    Inactive ingredients: acacia, anhydrous dibasic calcium phosphate, lactose monohydrate, magnesium stearate, starch, corn, silicon dioxide, talc

    FDA label

  • NorthStar Rx5 mg

    Has lactose · Made by Zydus Lifesciences

    Product page on northstarrxllc.com

    How it looks, what’s in it, NDCs

    5 mg LIGHT YELLOW TO YELLOW, round, 7 mm, marked “1014”

    PackageNDC

    Inactive ingredients: cellulose, microcrystalline, croscarmellose sodium, hydroxypropyl cellulose (110000 wamw), lactose monohydrate, magnesium stearate, silicon dioxide

    FDA label

  • Padagis5 mg

    Made by Novax Pro Pharma

    Product page on padagis.com

    Packages and NDCs

    5 mg

    PackageNDC
    Carton of 300574-1850-30
  • Zydus Lifesciences5 mg

    Has lactose

    How it looks, what’s in it, NDCs

    5 mg LIGHT YELLOW TO YELLOW, round, 7 mm, marked “1014”

    PackageNDC

    Inactive ingredients: cellulose, microcrystalline, croscarmellose sodium, hydroxypropyl cellulose (110000 wamw), lactose monohydrate, magnesium stearate, silicon dioxide

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

Phytonadione is a vitamin K replacement indicated for the treatment of adults with the following coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity:

  • Anticoagulant-induced prothrombin deficiency caused by coumarin or indanedione derivatives;
  • Hypoprothrombinemia secondary to antibacterial therapy;
  • Hypoprothrombinemia secondary to factors limiting absorption or synthesis of vitamin K, e.g., obstructive jaundice, biliary fistula, sprue, ulcerative colitis, celiac disease, intestinal resection, cystic fibrosis of the pancreas, and regional enteritis;
  • Other drug-induced hypoprothrombinemia where it is definitively shown that the result is due to interference with vitamin K metabolism, e.g., salicylates.

Source: the FDA label for Phytonadione (Northstar Rx LLC.), August 5, 2024. Full label on DailyMed