Myalept

Generic name: metreleptin

Used for: Leptin deficiency in generalized lipodystrophy

How do you pay?

How to pay the least

Ask for the cash price

Myalept

Myalept is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Myalept’s cash price, and one or two other pharmacies too.
  2. Myalept’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameMyalept
Authorized genericmetreleptin
Regular genericmetreleptin
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Myalept?
The original
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–

Brand nameThe maker’s card

Myalept Copay Program (Chiesi Total Care)

Savings card from Chiesi

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a prescription

The card takes up to $10,000 a year off your co-pay.

Sign up on chiesitotalcare.com 

Or call 1-855-669-2537.

In the maker’s words

“You may pay as little as $0 for your prescription.”

From the maker’s offer on chiesitotalcare.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Myalept itself, from the same company, sold without the brand name, and usually for less. For now Myalept is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Myalept is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

MYALEPT is a leptin analog indicated as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy.

Limitations of Use

  • The safety and effectiveness of MYALEPT for the treatment of complications of partial lipodystrophy have not been established.
  • The safety and effectiveness of MYALEPT for the treatment of liver disease, including nonalcoholic steatohepatitis (NASH), have not been established.
  • MYALEPT is not indicated for use in patients with HIV-related lipodystrophy.
  • MYALEPT is not indicated for use in patients with metabolic disease, without concurrent evidence of generalized lipodystrophy.

Source: the FDA label for Myalept (Chiesi USA, Inc.), March 25, 2024. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/myalept/