Mytesi savings card: as little as $0 a fill with commercial insurance

How to pay the least

Ask for the cash price

Mytesi

We didn’t find one.

Ask your pharmacy for Mytesi’s cash price, and one or two other pharmacies too.
Mytesi’s savings card works only with insurance from a job or one you bought.

Compare every option

Brand nameMytesi

Authorized genericcrofelemer

Regular genericcrofelemer

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldNone found

Same as Mytesi?

The original

–

Brand nameThe maker’s card

Mytesi Copay Savings Program (THERA patient support)

Savings card from Napo Pharmaceuticals

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 a fill

In the maker’s words

“Most eligible commercially insured patients may pay as little as $0 for Mytesi® (crofelemer), regardless of days of therapy dispensed, subject to restrictions, including maximum annual limit.”

From the maker’s offer on mytesi.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Mytesi itself, from the same company, sold without the brand name, and usually for less. For now Mytesi is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Diarrhea in people with HIV

What the FDA label says

MYTESI is an anti-diarrheal indicated for the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on anti-retroviral therapy.

Source: the FDA label for Mytesi (Napo Pharmaceuticals, Inc.), July 31, 2026. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/mytesi/