How do you pay?

How to pay the least

Ask for the cash price

Authorized generic

Natazia itself, without the brand name. It usually costs less than Natazia.

  1. Ask your pharmacy for the cash price of Natazia’s authorized generic. Its NDC is on this page; the pharmacy may need to order it.See its NDC
  2. Ask for Natazia’s cash price too, and pick the lower one.

Has to be Natazia? Bayer Savings Card takes up to $75 off a prescription without insurance.

Sign up on savingscard.bayer.com 

Free from the maker, if you qualify Bayer US Patient Assistance Foundation. Effective January 1, 2025, the financial eligibility requirement is 300% Federal Poverty Limit (FPL) for most Bayer prescription medications. Or call 1-866-228-7723.

See if you qualify 

None is sold. The authorized generic is the only generic.

Compare every option

Question
Brand nameNatazia
Authorized genericestradiol valerate and dienogest
Regular genericestradiol valerate and dienogest
What you’d pay
Up to$75 offa prescription with the maker’s card
Cash priceAsk the pharmacyOften less than Natazia
Not soldNone sold
Same as Natazia?
The original
Same medicine
–

Brand nameThe maker’s card

Natazia’s maker has a savings card that lowers what you pay at the pharmacy.

Bayer Savings Card

Savings card from Bayer

No insurance · up to $75 off a prescription
Insurance · as little as $0 a month

The card takes up to $125 a month off your co-pay.

Sign up on savingscard.bayer.com 

Or call 1-866-203-3503. See the offer on savingscard.bayer.com

In the maker’s words

“Pay as little as $0 up to a…”

“Up to $75 off each prescription for all other patients…”

From the maker’s offer on savingscard.bayer.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericThe NDC to ask for

The same medicine as Natazia, without the brand name. Give the pharmacy its NDC to get it.

estradiol valerate and dienogest

Sold by
  • SandozMade for Bayer HealthCare Pharmaceuticals, the company behind Natazia

Before you go

This authorized generic may not be on pharmacy shelves yet. Your pharmacy can check.

NDC to ask for
  • 4-phase packkit
    • 0781-4110-1511-digit: 00781-4110-153 blister packs per package

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Natazia, can you tell me what I’d pay for the brand, for the authorized generic from Sandoz (NDC 0781-4110-15)?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Natazia.

BrandNatazia
Authorized genericSandoz
See the ingredients

Active: estradiol valerate 3 mg · estradiol valerate 2 mg · dienogest 2 mg · estradiol valerate 2 mg · dienogest 3 mg · estradiol valerate 1 mg

Inactive, on both labels:

  • Ferric oxide red
  • Ferric oxide yellow
  • Hypromellose
  • Lactose monohydrate
  • Magnesium stearate
  • Polyethylene glycol 6000
  • Povidone k25
  • Corn starch
  • Talc
  • Titanium dioxide

Regular genericNot sold

None is sold. The authorized generic is the only generic. Generics usually come once the brand’s patents and exclusivity end. Until then, the authorized generic is the lower-cost way to get Natazia.

See the authorized generic →

What it’s used for

What the FDA label says
  • Natazia is a combination of dienogest, a progestin, and estradiol valerate, an estrogen, indicated for use by females of reproductive potential to prevent pregnancy.
  • The efficacy of Natazia in females of reproductive potential with a body mass index (BMI) of >30 kg/m2 has not been evaluated.
  • Treatment of heavy menstrual bleeding in females of reproductive potential without organic pathology who choose to use an oral contraceptive as their method of contraception.

Source: the FDA label for Natazia (Bayer HealthCare Pharmaceuticals Inc.), June 26, 2024. Full label on DailyMed 

Good to know