How to pay the least
Ask for the cash price
Generic pentamidine isethionate
No pharmacy we check posts a price for it.
- Ask your pharmacy for the cash price of generic pentamidine isethionate.Find pharmacies near you
- Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.
A regular generic has the same active ingredient as NebuPent, and the FDA requires it to work the same way.
Compare every option
Details for each option
Brand nameNo maker’s card
We didn’t find a savings card or cash price from NebuPent’s maker. Ask the pharmacy for NebuPent’s cash price. With insurance, ask what your plan charges.
Authorized genericNot sold
There isn’t one. An authorized generic is NebuPent itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.
Regular genericWho makes it
3 companies sell a generic of NebuPent that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.
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PAI Pharma300 mg
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Seton Pharmaceuticals300 mg
Made by PAI Pharma
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XGen Pharmaceuticals DJB300 mg/6 mL
Made by X Gen Pharmaceuticals
Product page on xgenpharmadjb.com
Packages and NDCs
300 mg/6 mL
Package NDC Carton of 6 mL 39822-3030-2
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What to say at the pharmacy
“Before you fill my NebuPent, can you tell me what I’d pay for the brand and for a generic?”
Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.
What it’s used for
What the FDA label says
INDICATIONS AND USAGE:
NebuPent is indicated for the prevention of Pneumocystis jiroveci pneumonia (PJP) in high-risk, HIV-infected patients defined by one or both of the following criteria:
i. a history of one or more episodes of PJP
ii. a peripheral CD4+ (T4 helper/inducer) lymphocyte count less than or equal to 200/mm3.
These indications are based on the results of an 18-month randomized, dose-response trial in high risk HIV-infected patients and on existing epidemiological data from natural history studies.
The patient population of the controlled trial consisted of 408 patients, 237 of whom had a history of one or more episodes of PJP. The remaining patients without a history of PJP included 55 patients with Kaposi’s sarcoma and 116 patients with other AIDS diagnoses, ARC or asymptomatic HIV infection. Patients were randomly assigned to receive NebuPent via the Respirgard® II nebulizer at one of the following three doses: 30 mg every two weeks (n=135), 150 mg every two weeks (n=134) or 300 mg every four weeks (n=139). The results of the trial demonstrated a significant protective effect (p<0.01) against PJP with the 300 mg every four week dosage regimen compared to the 30 mg every two week dosage regimen. The 300 mg dose regimen reduced the risk of developing PJP by 50 to 70% compared to the 30 mg regimen. A total of 293 patients (72% of all patients) also received zidovudine at sometime during the trial. The analysis of the data demonstrated the efficacy of the 300 mg dose even after adjusting for the effect of zidovudine.
The results of the trial further demonstrate that the dose and frequency of dosing are important to the efficacy of NebuPent prophylaxis in that multiple analyses consistently demonstrated a trend toward greater efficacy with 300 mg every four weeks as compared to 150 mg every two weeks.
No dose-response was observed for reduction in overall mortality; however, mortality from PJP was low in all three dosage groups.
Source: the FDA label for NebuPent (Fresenius Kabi USA, LLC), October 15, 2024. Full label on DailyMed
Good to know
- A regular generic may look different from NebuPent. The FDA requires it to work the same way.
- We didn’t find a savings card from NebuPent’s maker.
- Don’t stop or change a medicine without talking to your pharmacist or prescriber.
Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/nebupent/