Nucala

Generic name: mepolizumab

Used for: Severe asthma (eosinophilic type) · Chronic sinusitis with nasal polyps · Eosinophilic COPD (chronic lung disease) · Eosinophilic granulomatosis with polyangiitis (EGPA) · Hypereosinophilic syndrome (HES) · 4 more

How do you pay?

How to pay the least

Ask for the cash price

Nucala

Nucala is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Nucala’s cash price, and one or two other pharmacies too.
  2. Nucala’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify GSK Patient Assistance Program (prescription medicines). Or call 1-866-728-4368.

See if you qualify 

Compare every option

Question
Brand nameNucala
Authorized genericmepolizumab
Regular genericmepolizumab
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Nucala?
The original
–
–

Brand nameThe maker’s card

NUCALA Copay Program

Savings card from GSK

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a dose

Sign up on nucalacopayprogram.com 

Or call 1-800-691-1939.

In the maker’s words

“Eligible, commercially insured patients may pay as little as $0 for NUCALA…”

From the maker’s offer on nucalacopayprogram.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Nucala itself, from the same company, sold without the brand name, and usually for less. For now Nucala is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Nucala is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

NUCALA is an interleukin-5 (IL-5) antagonist monoclonal antibody (IgG1 kappa) indicated for:

  • Add-on maintenance treatment of adult and pediatric patients aged 6 years and older with severe asthma and with an eosinophilic phenotype.
  • Add-on maintenance treatment of adult patients aged 18 years and older with chronic rhinosinusitis with nasal polyps (CRSwNP).
  • Add-on maintenance treatment of adult patients with inadequately controlled chronic obstructive pulmonary disease (COPD) and an eosinophilic phenotype.
  • The treatment of adult patients with eosinophilic granulomatosis with polyangiitis (EGPA).
  • The treatment of adult and pediatric patients aged 12 years and older with hypereosinophilic syndrome (HES) for greater than or equal to 6 months without an identifiable non-hematologic secondary cause.

Limitations of use: Not for relief of acute bronchospasm or status asthmaticus.

Source: the FDA label for Nucala (GlaxoSmithKline LLC), August 6, 2025. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/nucala/