Numbrino vs. its authorized generic and generics

Numbrino is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How to pay the least

Given by your care team

Billed by the clinic

Numbrino is given by a doctor or nurse, not picked up at a pharmacy.

Ask your care team or your plan what you’d pay before your visit.

Compare every option

Brand nameNumbrino

Authorized genericcocaine

Regular genericcocaine

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyOften less than Numbrino

Not soldNone sold

Same as Numbrino?

The original

Same medicine

–

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Numbrino’s maker. Ask the pharmacy for Numbrino’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Numbrino, without the brand name. Give the pharmacy its NDC to get it.

cocaine

Sold by

Omnivium PharmaceuticalsThe company behind Numbrino

Given by your care team

Your doctor applies this during a nasal procedure. It isn’t something you pick up at a pharmacy.

NDC (for your care team)

4%solution
- 81665-301-0211-digit: 81665-0301-024 mL per bottle

Source: FDA, updated October 30, 2026

What to ask your care team

“Which version of Numbrino do you use: the brand, the authorized generic? What would I pay for each?”

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Numbrino.

Authorized generic package label from Omnivium Pharmaceuticals — Authorized genericOmnivium Pharmaceuticals

See the ingredients

Active: cocaine hydrochloride 4%

Inactive, on both labels:

Citric acid monohydrate
D&C Yellow No. 10
FD&C Green No. 3
Sodium benzoate
Water

Regular genericNot sold

None is sold. The authorized generic is the only generic. Generics usually come once the brand’s patents and exclusivity end. Until then, the authorized generic is the lower-cost way to get Numbrino.

See the authorized generic →

What it’s used for

Numbing the inside of the nose for procedures or surgery

What the FDA label says

NUMBRINO (cocaine hydrochloride) nasal solution is an ester local anesthetic indicated for the introduction of local anesthesia of the mucous membranes for diagnostic procedures and surgeries on or through the nasal cavities of adults.

Source: the FDA label for Numbrino (OMNIVIUM PHARMACEUTICALS LLC.), January 12, 2026. Full label on DailyMed

Good to know

It may look different from Numbrino (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Coverage depends on your plan. Your care team or insurer can tell you what you’d pay.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/numbrino/