Onivyde is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Onivyde is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameOnivyde
Authorized genericirinotecan
Regular genericirinotecan
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Onivyde?
The original
–
–

Brand nameThe maker’s card

Onivyde Copay Assistance Program (IPSEN CARES)

Savings card from Ipsen

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a prescription

Sign up on ipsencares.com 

In the maker’s words

“If you have been prescribed Onivyde and you have commercial (private) insurance, you may be eligible to receive copay assistance and pay as little as $0 per prescription for Onivyde.”

From the maker’s offer on ipsencares.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Onivyde itself, from the same company, sold without the brand name, and usually for less. For now Onivyde is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

ONIVYDE is a topoisomerase inhibitor indicated:

  • in combination with oxaliplatin, fluorouracil and leucovorin, for the first-line treatment of adult patients with metastatic pancreatic adenocarcinoma,
  • in combination with fluorouracil and leucovorin, for the treatment of adult patients with metastatic pancreatic adenocarcinoma after disease progression following gemcitabine-based therapy.

Limitation of Use: ONIVYDE is not indicated as a single agent for the treatment of patients with metastatic pancreatic adenocarcinoma.

Source: the FDA label for Onivyde (Ipsen Biopharmaceuticals, Inc.), March 3, 2025. Full label on DailyMed 

Good to know