How do you pay?

How to pay the least

Ask for the cash price

Opfolda

We didn’t find one.

  1. Ask your pharmacy for Opfolda’s cash price, and one or two other pharmacies too.
  2. Opfolda’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameOpfolda
Authorized genericmiglustat
Regular genericmiglustat
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Opfolda?
The original
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–

Brand nameThe maker’s card

AMICUS ASSIST Co-Pay Assistance

Savings card from Amicus Therapeutics

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a month

Sign up on pombilitiopfoldahcp.com 

Or call 1-833-264-2872.

In the maker’s words

“Eligible commercially or privately insured patients may pay as little as $0 per month for treatment…”

From the maker’s offer on pombilitiopfoldahcp.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Brand nameWith a free discount coupon

Optum Perks, Optum’s free discount coupon, lists these prices for Opfolda without insurance. Show the coupon from its page at the pharmacy; it can’t be used with insurance.

From Optum Perks, read November 2, 2026, with no location set. Its page opens on this dose; other doses and pharmacies near you are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold

There isn’t one. An authorized generic is Opfolda itself, from the same company, sold without the brand name, and usually for less. For now Opfolda is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

OPFOLDA is an enzyme stabilizer indicated, in combination with Pombiliti, a hydrolytic lysosomal glycogen-specific enzyme, for the treatment of adult patients with late-onset Pompe disease (lysosomal acid alpha-glucosidase [GAA] deficiency) weighing ≥40 kg and who are not improving on their current enzyme replacement therapy (ERT).

Source: the FDA label for Opfolda (AMICUS THERAPEUTICS US, LLC), November 27, 2024. Full label on DailyMed 

Good to know