Generic name: macitentan
Used for: High blood pressure in the lungs (PAH)
Lowest price
$67.76 for 30 tablets delivered ($62.51 plus $5.25 shipping)
Generic macitentan 10 mg from Cost Plus Drugs, by mail
A regular generic has the same active ingredient as Opsumit, and the FDA requires it to work the same way.
Details for each option
Savings card from Johnson & Johnson
Or call 1-833-742-0791.
“Eligible patients pay $5 per prescription fill.”
From the maker’s offer on jnjwithme.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.
There isn’t one. An authorized generic is Opsumit itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.
Pharmacies’ own cash prices for generic macitentan, lowest first.
Delivered
From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.
Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.
10 companies sell a generic of Opsumit that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.
Has lactose
10 mg White to off white, round, 5 mm, marked “L / 11”
| Package | NDC |
|---|---|
| Bottle of 30 | 62332-373-30 |
Inactive ingredients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, poloxamer 188, povidone, sodium stearyl fumarate, polyvinyl alcohol, titanium dioxide, talc, lecithin, soybean, xanthan gum
10 mg White to off white, round, 6 mm, marked “APO / M / 10”
| Package | NDC |
|---|---|
| Carton of 30 | 60505-4644-3 |
Inactive ingredients: microcrystalline cellulose, magnesium stearate, polyvinyl alcohol, talc, titanium dioxide, polyethylene glycol 8000, croscarmellose sodium
Has lactose
10 mg White to off-white, round, 6 mm, marked “N / 3”
| Package | NDC |
|---|---|
| Bottle of 30 | 59651-147-30 |
Inactive ingredients: lactose monohydrate, lecithin, soybean, polysorbate 80, polyvinyl alcohol, povidone k30, sodium starch glycolate type a potato, sodium stearyl fumarate, talc, titanium dioxide, xanthan gum
10 mg White to off white, round, 6 mm, marked “L1”
| Package | NDC |
|---|---|
| Carton of 15 | 42385-907-15 |
| Bottle of 30 | 42385-907-30 |
Inactive ingredients: crospovidone (120 .mu.m), mannitol, magnesium stearate, microcrystalline cellulose, polysorbate 80, povidone k30, polyvinyl alcohol, soybean lecithin, talc, titanium dioxide, xanthan gum
Has lactose
10 mg White, round, 6 mm, marked “M / MC / 10”
| Package | NDC |
|---|---|
| Bottle of 30 | 0378-0606-93 |
Inactive ingredients: glyceryl mono- and dicaprylocaprate, lactose monohydrate, microcrystalline cellulose 101, polysorbate 80, polyvinyl alcohol, povidone k30, sodium lauryl sulfate, sodium starch glycolate type a potato, sodium stearyl fumarate, talc, titanium dioxide
Made by Lepu Pharmaceutical Technology
10 mg White, round, 6 mm, marked “M”
| Package | NDC |
|---|---|
| Carton of 15 | 82293-041-10 |
| Bottle of 30 | 82293-041-20 |
| Bottle of 100 | 82293-041-30 |
Inactive ingredients: soybean lecithin, magnesium stearate, mannitol, microcrystalline cellulose, povidone, polysorbate 80, polyvinyl alcohol, sodium starch glycolate type a potato, talc, titanium dioxide, xanthan gum
Has lactose · Made by MSN Laboratories
10 mg White, round, 6 mm, marked “M / 10”
| Package | NDC |
|---|---|
| Bottle of 30 | 0781-8135-31 |
Inactive ingredients: lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone k30, sodium starch glycolate type a potato, sodium lauryl sulfate, polyvinyl alcohol, soybean lecithin, talc, titanium dioxide, xanthan gum
10 mg Off-white, round, 6 mm, marked “M1”
| Package | NDC |
|---|---|
| Carton of 15 | 47335-070-15 |
| Carton of 30 | 47335-070-30 |
Inactive ingredients: mannitol, microcrystalline cellulose 101, povidone k30, crospovidone (15 mpa.s at 5%), polysorbate 80, magnesium stearate, polyvinyl alcohol, lecithin, soybean, titanium dioxide, talc, xanthan gum
10 mg White, round, 5 mm, marked “TV / J7”
| Package | NDC |
|---|---|
| Bottle of 30 | 0480-0915-56 |
Inactive ingredients: microcrystalline cellulose 101, microcrystalline cellulose 102, povidone k30
10 mg White to off white colored, round, 6 mm, marked “J5”
| Package | NDC |
|---|---|
| Bottle of 30 | 13668-542-30 |
| Bottle of 90 | 13668-542-90 |
| Bottle of 500 | 13668-542-05 |
Inactive ingredients: microcrystalline cellulose 102, succinimidyl-4-(n-maleimidomethyl)cyclohexane-1-carboxylate, sodium starch glycolate type a potato, povidone k30, polysorbate 80, magnesium stearate, mannitol, titanium dioxide, talc, lecithin, soybean, xanthan gum, polyvinyl alcohol
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
“Before you fill my Opsumit, can you tell me what I’d pay for the brand and for a generic?”
Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.
OPSUMIT is an endothelin receptor antagonist (ERA) indicated for the treatment of pulmonary arterial hypertension (PAH, WHO Group I) in adults to reduce the risks of disease progression and hospitalization for PAH.
Source: the FDA label for Opsumit (Actelion Pharmaceuticals US, Inc.), April 11, 2025. Full label on DailyMed
Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/opsumit/