Brand-name prescription

Opzelura

ruxolitinib

Compare your options

Compare	OpzeluraBrand name	Authorized genericWithout the Opzelura name	Regular genericruxolitinib
What pharmacies pay	$2,041per 60 g tube	Not sold	Not sold
Same as Opzelura?	The original	–	–
Ways to save	Maker’s cardas little as $0 a tubewith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: No generic is sold yet.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Incyte

OPZELURA Copay Savings Program

With commercial insurance

as little as $0 a tube

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

Get it on opzelura.com

In the maker’s words

“By using this copay savings card at participating pharmacies, eligible patients with commercial prescription drug insurance coverage for OPZELURA may pay as little as $0 per tube.”

From the maker’s offer on opzelura.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Opzelura’s own card may bring it to as little as $0 a tube.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Opzelura
1.5% creamper 60 g tube	$2,041

Good to know

There’s no authorized generic of Opzelura.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.