Generic name: nitisinone
Used for: Hereditary tyrosinemia type 1 (HT-1)
From
$797.28 for 30 capsules delivered ($792.03 plus $5.25 shipping)
Generic nitisinone from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.
Need it today? From $5,077.53 for 30 capsules with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.
See the price and get the cardA regular generic has the same active ingredient as Orfadin, and the FDA requires it to work the same way.
Details for each option
Savings card from Sobi (Swedish Orphan Biovitrum)
The card takes up to $10,000 a year off your co-pay.
“As little as $0 co-pay for eligible patients…”
From the maker’s offer on orfadin.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.
There isn’t one. An authorized generic is Orfadin itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.
Pharmacies’ own cash prices for generic nitisinone, lowest first.
Pick up in storeDelivered
From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.
Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.
3 companies sell a generic of Orfadin that the FDA rates a substitute. A pharmacy fills whichever one it stocks. One of them has its own savings card, listed first. It works only with that maker’s version. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.
Has lactose
Eton Cares (Nitisinone)
With commercial insurance as little as $0
“Eton Cares can help eligible, commercially insured patients get their medication for as little as $0 per month.”
2 mg White opaque cap filled with white to off-white powder, capsule, 3 mm
| Package | NDC |
|---|---|
| Carton of 60 | 71863-119-60 |
5 mg White opaque cap filled with white to off-white powder, capsule, 3 mm
| Package | NDC |
|---|---|
| Carton of 60 | 71863-120-60 |
10 mg White opaque cap filled with white to off-white powder, capsule, 3 mm
| Package | NDC |
|---|---|
| Carton of 60 | 71863-121-60 |
20 mg White opaque cap filled with white to off-white powder, capsule, 3 mm
| Package | NDC |
|---|---|
| Carton of 60 | 71863-122-60 |
Inactive ingredients: stearic acid, anhydrous lactose
Has a dye: FD&C Blue No. 2--aluminum lake · Made by Medunik Canada
2 mg White, capsule, 16 mm, marked “2 / logo”
| Package | NDC |
|---|---|
| Carton of 60 | 70505-202-60 |
5 mg White, capsule, 16 mm, marked “5 / logo”
| Package | NDC |
|---|---|
| Carton of 60 | 70505-205-60 |
10 mg White, capsule, 18 mm, marked “10 / logo”
| Package | NDC |
|---|---|
| Carton of 60 | 70505-210-60 |
20 mg White, capsule, 18 mm, marked “20 / logo”
| Package | NDC |
|---|---|
| Carton of 60 | 70505-220-60 |
Inactive ingredients: modified corn starch (1-octenyl succinic anhydride), gelatin, stearic acid, titanium dioxide, FD&C Blue No. 2--aluminum lake, shellac, propylene glycol, ammonia
Made by Novitium Pharma
2 mg White, capsule, 16 mm, marked “008 / Novitium2mg”
| Package | NDC |
|---|---|
| Carton of 60 | 0254-3020-02 |
5 mg White, capsule, 16 mm, marked “009 / Novitium5mg”
| Package | NDC |
|---|---|
| Carton of 60 | 0254-3021-02 |
10 mg White, capsule, 16 mm, marked “010 / Novitium10mg”
| Package | NDC |
|---|---|
| Carton of 60 | 0254-3022-02 |
Inactive ingredients: anhydrous citric acid, propylene glycol, ammonia, hypromellose 2910 (5 mpa.s), mannitol, stearic acid, gelatin, sodium lauryl sulfate, titanium dioxide, ferrosoferric oxide, potassium hydroxide
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
“Before you fill my Orfadin, can you tell me what I’d pay for the brand and for a generic?”
Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.
ORFADIN is a hydroxy-phenylpyruvate dioxygenase inhibitor indicated for the treatment of adult and pediatric patients with hereditary tyrosinemia type 1 (HT-1) in combination with dietary restriction of tyrosine and phenylalanine.
Source: the FDA label for Orfadin (SWEDISH ORPHAN BIOVITRUM AB (PUBL)), November 30, 2021. Full label on DailyMed
Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/orfadin/