Brand-name prescription

Orfadin

nitisinone

Compare your options

Compare	OrfadinBrand name	Authorized genericWithout the Orfadin name	Regular genericnitisinone
What pharmacies pay	Price not listed	Not sold	Not sold
Same as Orfadin?	The original	–	–
Ways to save	Maker’s cardas little as $0 a fillwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: The FDA has approved a generic, but it isn’t in pharmacies yet. Ask your pharmacist.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Sobi (Swedish Orphan Biovitrum)

Orfadin4U Copay Program

With commercial insurance

as little as $0 a fill

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

The card pays up to $10,000 a year.

Get it on orfadin.com

In the maker’s words

“As little as $0 co-pay for eligible patients…”

From the maker’s offer on orfadin.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Orfadin’s own card may bring it to as little as $0 a fill.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

Good to know

There’s no authorized generic of Orfadin.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.