How do you pay?

How to pay the least

Ask for the cash price

Orlynvah

We didn’t find one.

  1. Ask your pharmacy for Orlynvah’s cash price, and one or two other pharmacies too.
  2. Orlynvah’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameOrlynvah
Authorized genericsulopenem etzadroxil and probenecid
Regular genericsulopenem etzadroxil and probenecid
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Orlynvah?
The original
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–

Brand nameThe maker’s card

ORLYNVAH Copay Savings Program

Savings card from Iterum Therapeutics

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $25 a prescription

Sign up on iterumtx.com 

In the maker’s words

“To support patient access, Iterum Therapeutics is launching a copay savings program allowing eligible patients to obtain ORLYNVAH™ for as little as $25.”

From the maker’s offer on iterumtx.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Orlynvah itself, from the same company, sold without the brand name, and usually for less. For now Orlynvah is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

ORLYNVAH, a combination of sulopenem etzadroxil, a penem antibacterial, and probenecid, a renal tubular transport inhibitor, is indicated for the treatment of uncomplicated urinary tract infections (uUTI) caused by the designated microorganisms Escherichia coli, Klebsiella pneumoniae, or Proteus mirabilis in adult women who have limited or no alternative oral antibacterial treatment options.

Limitations of Use

ORLYNVAH is not indicated for the treatment of:

  • Complicated urinary tract infections (cUTI) or as step-down treatment after intravenous antibacterial treatment of cUTI.
  • Complicated intra-abdominal infections (cIAI) or as step-down treatment after intravenous antibacterial treatment of cIAI.

Usage to Reduce Development of Drug-Resistant Bacteria

To reduce the development of drug-resistant bacteria and maintain the effectiveness of ORLYNVAH and other antibacterial drugs, ORLYNVAH should be used only to treat uUTI that are proven or strongly suspected to be caused by susceptible bacteria. Culture and susceptibility information should be utilized in selecting or modifying antibacterial therapy.

Source: the FDA label for Orlynvah (ITERUM THERAPEUTICS US LIMITED), December 6, 2025. Full label on DailyMed 

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