How do you pay?

How to pay the least

Cash price

$2,690+ for 30 tablets

Pharmacies pay about this for Otezla; you’d pay more.

  1. Ask your pharmacy for Otezla’s cash price, and one or two other pharmacies too.
  2. Otezla’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Amgen Safety Net Foundation. Amgen Safety Net Foundation income requirements are based on a percentage of the Federal Poverty Level, adjusted for household size. Or call 1-800-932-3060.

See if you qualify 

No generic is sold yet.

Compare every option

Question
Brand nameOtezla
Authorized genericapremilast
Regular genericapremilast
What you’d pay
At least$2,690for 30 tablets; pharmacies pay this
Not soldThere isn’t one
Not soldNone sold yet
Same as Otezla?
The original
–
–

Brand nameThe maker’s card

Otezla Co-Pay Program (Amgen SupportPlus)

Savings card from Amgen

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a month

Sign up on otezla.com 

See the offer on otezla.com

In the maker’s words

“You may pay as little as $0 out-of-pocket per month for Otezla.”

From the maker’s offer on otezla.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Brand nameTrumpRx.gov price

TrumpRx.gov, the federal government’s drug price site, lists Otezla at a price its maker agreed to, for people paying without insurance.

From TrumpRx.gov, read October 28, 2026. Its page opens on this price; other strengths and amounts are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold

There isn’t one. An authorized generic is Otezla itself, from the same company, sold without the brand name, and usually for less. For now Otezla is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

OTEZLA/OTEZLA XR, an inhibitor of phosphodiesterase 4 (PDE4), is indicated for the treatment of:

Adult patients with:

  • Active psoriatic arthritis
  • Plaque psoriasis who are candidates for phototherapy or systemic therapy
  • Oral ulcers associated with Behçet's Disease

Pediatric patients 6 years of age and older with:

  • Active psoriatic arthritis
  • Moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy

In the pediatric population, OTEZLA is indicated for patients weighing at least 20 kg, and OTEZLA XR is indicated for patients weighing at least 50 kg.

Source: the FDA label for Otezla (Amgen, Inc), September 2, 2026. Full label on DailyMed 

Good to know