Pemrydi Rtu is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Pemrydi Rtu is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand namePemrydi Rtu
Authorized genericpemetrexed disodium
Regular genericpemetrexed disodium
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Pemrydi Rtu?
The original
–
–

Brand nameThe maker’s card

Amneal PATHways Co-Pay Assistance Card

Savings card from Amneal Pharmaceuticals

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a treatment

Sign up on pemrydi.us 

Or call 1-866-426-6325.

In the maker’s words

“Eligible commercially insured patients may pay as little as $0 per treatment with an Amneal product.”

From the maker’s offer on pemrydi.us, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Pemrydi Rtu itself, from the same company, sold without the brand name, and usually for less. For now Pemrydi Rtu is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

PEMRYDI RTU® is a folate analog metabolic inhibitor indicated:

  • in combination with pembrolizumab and platinum chemotherapy, for the initial treatment of patients with metastatic non-squamous non-small cell lung cancer (NSCLC), with no EGFR or ALK genomic tumor aberrations.
  • in combination with cisplatin for the initial treatment of patients with locally advanced or metastatic, non-squamous NSCLC.
  • as a single agent for the maintenance treatment of patients with locally advanced or metastatic, non-squamous NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy.
  • as a single agent for the treatment of patients with recurrent, metastatic non-squamous, NSCLC after prior chemotherapy. Limitations of Use: PEMRYDI RTU is not indicated for the treatment of patients with squamous cell, non-small cell lung cancer.
  • initial treatment, in combination with cisplatin, of patients with malignant pleural mesothelioma whose disease is unresectable or who are otherwise not candidates for curative surgery.

Source: the FDA label for Pemrydi Rtu (Amneal Pharmaceuticals LLC), July 8, 2025. Full label on DailyMed 

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