How do you pay?

How to pay the least

Cash price

$1,820+ for 30 tablets

Pharmacies pay about this for Pifeltro; you’d pay more.

  1. Ask your pharmacy for Pifeltro’s cash price, and one or two other pharmacies too.
  2. Pifeltro’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Merck Patient Assistance Program. You may qualify for the program if you have a household income of $63,840 or less for individuals, $86,560 or less for couples, or $132,000 or less for a family of 4. Or call 800-727-5400.

See if you qualify 

No generic is sold yet.

Compare every option

Question
Brand namePifeltro
Authorized genericdoravirine
Regular genericdoravirine
What you’d pay
At least$1,820for 30 tablets; pharmacies pay this
Not soldThere isn’t one
Not soldNone sold yet
Same as Pifeltro?
The original
–
–

Brand nameThe maker’s card

PIFELTRO Savings Coupon

Savings card from Merck

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a fill

The card takes up to $6,800 per patient off your co-pay.

Sign up on pifeltro.com 

In the maker’s words

“Eligible, privately insured patients may pay as little as $0 in out-of-pocket costs, up to a total program savings of $6,800.”

From the maker’s offer on pifeltro.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Pifeltro itself, from the same company, sold without the brand name, and usually for less. For now Pifeltro is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

PIFELTRO, a non-nucleoside reverse transcriptase inhibitor (NNRTI), is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 35 kg:

  • with no prior antiretroviral treatment history, OR
  • to replace the current antiretroviral regimen in those who are virologically-suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen with no history of treatment failure and no known substitutions associated with resistance to doravirine.

Source: the FDA label for Pifeltro (Merck Sharp & Dohme LLC), July 8, 2026. Full label on DailyMed 

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