How do you pay?

How to pay the least

Lowest without a membership

$12.22 for 30 tablets delivered ($6.97 plus $5.25 shipping)

Generic hydroxychloroquine 200 mg from Cost Plus Drugs, by mail

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic hydroxychloroquine 200 mg. It comes by mail.

With a membership $8.90 for 30 tablets from Amazon Pharmacy, by mail ($139 a year).

Open Amazon Pharmacy 

A regular generic has the same active ingredient as Plaquenil, and the FDA requires it to work the same way.

Compare every option

Question
Brand namePlaquenil
Authorized generichydroxychloroquine
Regular generichydroxychloroquine
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Not soldNo longer sold
Lowest$12.22for 30 tablets at Cost Plus Drugs, with shipping
Same as Plaquenil?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameWith a free discount coupon

Optum Perks, Optum’s free discount coupon, lists these prices for Plaquenil without insurance. Show the coupon from its page at the pharmacy; it can’t be used with insurance.

From Optum Perks, read November 2, 2026, with no location set. Its page opens on this dose; other doses and pharmacies near you are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold now

An authorized generic of Plaquenil was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (hydroxychloroquine sulfate) is available.

Source: FDA, updated October 30, 2026

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic hydroxychloroquine, lowest first.

Pick up in storeDelivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

10 companies sell a generic of Plaquenil that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Accord Healthcare200 mg

    Has lactose

    Product page on accordhealthcare.us

    How it looks, what’s in it, NDCs

    200 mg White, double circle, 13 mm, marked “H11”

    PackageNDC
    Bottle of 10016729-485-01
    Bottle of 50016729-485-16

    Inactive ingredients: lactose monohydrate, starch, corn, magnesium stearate, povidone k30, polyethylene glycol 4000, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • Amneal Pharmaceuticals200 mg
    How it looks, what’s in it, NDCs

    200 mg White to off-white, capsule, 13 mm, marked “AC54”

    PackageNDC
    Bottle of 10069238-1544-1
    Bottle of 50069238-1544-5

    Inactive ingredients: croscarmellose sodium, dibasic calcium phosphate dihydrate, magnesium stearate, polyethylene glycol 3350, polyvinyl alcohol, sodium lauryl sulfate, starch, corn, talc, titanium dioxide

    FDA label

  • Aurobindo Pharma200 mg

    Has lactose

    Product page on aurobindousa.com

    How it looks, what’s in it, NDCs

    200 mg White, round, 10 mm, marked “C”

    PackageNDC
    Bottle of 10059651-889-01
    Bottle of 50059651-889-05

    Inactive ingredients: anhydrous lactose, croscarmellose sodium, hypromellose 2910 (6 mpa.s), hypromellose 2910 (3 mpa.s), hypromellose 2910 (50 mpa.s), magnesium stearate, microcrystalline cellulose, polydextrose, polyethylene glycol 8000, povidone k30, sodium lauryl sulfate, titanium dioxide, triacetin

    FDA label

  • Chartwell RX200 mg

    Has lactose

    How it looks, what’s in it, NDCs

    200 mg White to off white, oval, 13 mm, marked “CE / 173”

    PackageNDC
    Bottle of 9062135-752-90

    Inactive ingredients: silicon dioxide, crospovidone, hypromellose, lactose monohydrate, silodrate, magnesium stearate, polyethylene glycol, povidone, talc, titanium dioxide

    FDA label

  • Dr. Reddy’s Laboratories200 mg

    Has lactose · Made by Appco Pharma

    How it looks, what’s in it, NDCs

    200 mg White to off-white, oval, 12 mm, marked “AC / 384”

    PackageNDC
    Bottle of 10043598-721-01
    Bottle of 50043598-721-05

    Inactive ingredients: crospovidone, hypromellose, lactose monohydrate, magnesium stearate, polyethylene glycol, polyvinyl alcohol, starch, corn, talc, titanium dioxide

    FDA label

  • Ipca Laboratories200 mg

    Product page on unichemusa.com

    How it looks, what’s in it, NDCs

    200 mg White, capsule, 14 mm, marked “HCQS”

    PackageNDC
    Bottle of 1083980-001-97
    Bottle of 10083980-001-01
    Bottle of 50083980-001-05
    Bottle of 100083980-001-10

    Inactive ingredients: anhydrous dibasic calcium phosphate, hypromellose, magnesium stearate, polyethylene glycol 3350, polysorbate 80, silicon dioxide, starch, corn, talc, titanium dioxide

    FDA label

  • NorthStar Rx200 mg

    Made by Zydus Lifesciences

    Product page on northstarrxllc.com

    How it looks, what’s in it, NDCs

    200 mg WHITE TO OFF-WHITE, capsule, 13 mm, marked “ZC38”

    PackageNDC
    Bottle of 10016714-110-01
    Bottle of 50016714-110-02

    Inactive ingredients: dibasic calcium phosphate dihydrate, magnesium stearate, polyethylene glycol, polyvinyl alcohol, talc, titanium dioxide, starch, corn

    FDA label

  • Rising Pharma Holdings200 mg

    Has lactose · Made by Laurus Labs

    How it looks, what’s in it, NDCs

    200 mg White to Off White, capsule, 13 mm, marked “J2”

    PackageNDC
    Bottle of 6016571-112-06
    Bottle of 10016571-112-01
    Bottle of 50016571-112-50
    Bottle of 100016571-112-10

    Inactive ingredients: magnesium stearate, polyethylene glycol 8000, povidone, lactose monohydrate, starch, corn, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • Teva Pharmaceuticals200 mg

    Being phased out; sold until November 2026

    How it looks, what’s in it, NDCs

    200 mg White, oval, 13 mm, marked “TV / 2401”

    PackageNDC
    Bottle of 1000093-2401-01

    Inactive ingredients: calcium phosphate, dibasic, dihydrate, hypromellose 2910 (3 mpa.s), hypromellose 2910 (6 mpa.s), hypromellose 2910 (50 mpa.s), magnesium stearate, polydextrose, polyethylene glycol 8000, starch, corn, titanium dioxide, triacetin

    FDA label

  • Zydus Lifesciences200 mg
    How it looks, what’s in it, NDCs

    200 mg WHITE TO OFF-WHITE, oval, 13 mm, marked “ZC38”

    PackageNDC
    Bottle of 10068382-096-01
    Carton of 10068382-096-77
    Bottle of 50068382-096-05

    Inactive ingredients: dibasic calcium phosphate dihydrate, magnesium stearate, polyethylene glycol, polyvinyl alcohol, talc, titanium dioxide, starch, corn

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

PLAQUENIL is an antimalarial and antirheumatic indicated for the: • Treatment of uncomplicated malaria due to Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax in adult and pediatric patients. • Prophylaxis of malaria in geographic areas where chloroquine resistance is not reported in adult and pediatric patients. • Treatment of rheumatoid arthritis in adults. • Treatment of systemic lupus erythematosus in adults. • Treatment of chronic discoid lupus erythematosus in adults. Limitations of Use: PLAQUENIL is not recommended for the: • Treatment of complicated malaria. • Treatment of chloroquine or hydroxychloroquine-resistant strains of Plasmodium species. • Treatment of malaria acquired in geographic areas where chloroquine resistance occurs or when the Plasmodium species has not been identified. • Prophylaxis of malaria in geographic areas where chloroquine resistance occurs. • Prevention of relapses of P. vivax or P. ovale because it is not active against the hypnozoite liver stage forms of these parasites. For radical cure of P. vivax and P. ovale infections, concomitant therapy with an 8-aminoquinoline drug is necessary.

Source: the FDA label for Plaquenil (Advanz Pharma (US) Corp.), April 9, 2026. Full label on DailyMed