An authorized generic of Polytrim was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (polymyxin B sulfate and trimethoprim sulfate) is available.
Source: FDA, updated October 30, 2026
How to pay the least
Ask for the cash price
Generic polymyxin B and trimethoprim
No pharmacy we check posts a price for it.
- Ask your pharmacy for the cash price of generic polymyxin B and trimethoprim.Find pharmacies near you
- Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.
A regular generic has the same active ingredient as Polytrim, and the FDA requires it to work the same way.
Compare every option
Question
Brand namePolytrim
Authorized genericpolymyxin B and trimethoprim
Regular genericpolymyxin B and trimethoprim
What you’d pay
Not soldNo longer sold
Not soldNo longer sold
Cash priceAsk the pharmacy
Same as Polytrim?
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Same active ingredientFillers and dyes can differ
Details for each option
Details for
Brand nameNot sold
Polytrim itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.
Authorized genericNot sold now
Regular genericWho makes it
3 companies sell a generic of Polytrim that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
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Bausch & Lomb10,000 units/mL / 1 mg/mL
How it looks, what’s in it, NDCs
10,000 units/mL / 1 mg/mL
Package NDC Carton of 10 mL 24208-315-10 Inactive ingredients: water, sodium chloride, sulfuric acid, sodium hydroxide, benzalkonium chloride
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Sandoz10,000 units/mL / 1 mg/mL
How it looks, what’s in it, NDCs
10,000 units/mL / 1 mg/mL
Package NDC Carton of 10 mL 61314-628-10 Inactive ingredients: benzalkonium chloride, sodium chloride, sulfuric acid, water, sodium hydroxide
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Somerset Therapeutics10,000 units/mL / 1 mg/mL
Product page on somersetpharma.com
How it looks, what’s in it, NDCs
10,000 units/mL / 1 mg/mL A clear, colorless to pale yellow color solution
Package NDC Carton of 10 mL 70069-311-01 Inactive ingredients: sodium chloride, sulfuric acid, benzalkonium chloride, sodium hydroxide, water
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What it’s used for
What the FDA label says
Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution is indicated in the treatment of surface ocular bacterial infections, including acute bacterial conjunctivitis, and blepharoconjunctivitis, caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus viridans, Haemophilus influenzae and Pseudomonas aeruginosa.*
- Efficacy for this organism in this organ system was studied in fewer than 10 infections.
Source: the FDA label for Polymyxin B Sulfate and Trimethoprim (Sandoz Inc), September 5, 2025. Full label on DailyMed
Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/polytrim/