How do you pay?

How to pay the least

Ask for the cash price

Premphase

No generic is sold yet.

  1. Ask your pharmacy for Premphase’s cash price, and one or two other pharmacies too.

Free from the maker, if you qualify Pfizer Patient Assistance Program. Meet the income requirements – Your annual household pre-tax income cannot exceed 300% of the Federal Poverty Level, adjusted for household size. Or call 1-844-989-7284.

See if you qualify 

Compare every option

Question
Brand namePremphase
Authorized genericconjugated estrogens and medroxyprogesterone
Regular genericconjugated estrogens and medroxyprogesterone
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone sold yet
Same as Premphase?
The original
–
–

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Premphase’s maker. Ask the pharmacy for Premphase’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Premphase itself, from the same company, sold without the brand name, and usually for less. For now Premphase is the only choice; ask the pharmacy for its cash price, or your plan what it charges.

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, ask the pharmacy for Premphase’s cash price, or your plan what it charges.

What it’s used for

What the FDA label says

PREMPRO/PREMPHASE is an estrogen plus progestin indicated in a woman with a uterus for:

  • Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause
  • Treatment of Moderate to Severe Vulvar and Vaginal Atrophy due to Menopause
  • Prevention of Postmenopausal Osteoporosis

Source: the FDA label for Premphase (Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.), April 28, 2026. Full label on DailyMed 

Good to know