Brand-name prescription

Prempro

conjugated estrogens and medroxyprogesterone

Compare your options

Compare	PremproBrand name	Authorized genericWithout the Prempro name	Regular genericconjugated estrogens and medroxyprogesterone
What pharmacies pay	from$8.67–8.68per tablet	Not sold	Not sold
Same as Prempro?	The original	–	–
Ways to save	Maker’s cardup to $110 off a fillwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: No generic is sold yet.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Pfizer

Pfizer Menopause Hormone Therapy Co-Pay Savings Card

With commercial insurance

up to $110 off a fill

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

The card pays up to $1,440 a year.

Get it on pfizermenopause.com

In the maker’s words

“Prempro up to $110 savings…”

From the maker’s offer on pfizermenopause.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Prempro’s own card may bring it to up to $110 off a fill.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Prempro
0.3 mg-1.5 mg tabletper tablet	$8.68
0.45-1.5 mg tabletper tablet	$8.68
0.625-2.5 mg tabletper tablet	$8.68
0.625-5 mg tabletper tablet	$8.67

Good to know

There’s no authorized generic of Prempro.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.