How do you pay?

How to pay the least

From

$39.47 for 30 tablets delivered ($34.22 plus $5.25 shipping)

Generic darunavir from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic darunavir. It comes by mail.

Need it today? From $45.64 for 30 tablets with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card 

A regular generic has the same active ingredient as Prezista, and the FDA requires it to work the same way.

Compare every option

Question
Brand namePrezista
Authorized genericdarunavir
Regular genericdarunavir
What you’d pay
At least$1,040for 30 tablets; pharmacies pay this
Not soldThere isn’t one
From$39.47for 30 tablets at Cost Plus Drugs, with shipping
Same as Prezista?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

J&J withMe Savings Program

Savings card from Johnson & Johnson (Janssen)

No insuranceNeeds insuranceNo cash price listed.
Insurance $0 a fill

The card takes up to $7,500 a year off your co-pay.

Sign up on jnjwithme.com 

Or call 1-833-742-0791.

In the maker’s words

“Eligible patients with commercial or private insurance pay $0 each time you fill your prescription.”

From the maker’s offer on jnjwithme.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Prezista itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic darunavir, lowest first.

Pick up in storeDelivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

9 companies sell a generic of Prezista that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Amneal Pharmaceuticals600 mg, 800 mg

    Has a dye: FD&C Yellow No. 6

    How it looks, what’s in it, NDCs

    600 mg Orange, oval, 18 mm, marked “AC13”

    PackageNDC
    Carton of 6060219-1144-6

    800 mg Dark red, oval, 20 mm, marked “AC14”

    PackageNDC
    Carton of 3060219-1145-3

    Inactive ingredients: crospovidone (12 mpa.s at 5%), FD&C Yellow No. 6, hydroxypropyl cellulose, magnesium stearate, microcrystalline cellulose, polyvinyl alcohol, polyethylene glycol 3350, silicon dioxide, sodium starch glycolate type a potato, talc, titanium dioxide, ferric oxide red

    FDA label

  • Aurobindo Pharma600 mg, 800 mg

    Has a dye: FD&C Yellow No. 6

    Product page on aurobindousa.com

    How it looks, what’s in it, NDCs

    600 mg Orange, oval, 17 mm, marked “D / 600”

    PackageNDC
    Bottle of 6059651-085-60

    800 mg Dark Red, oval, 20 mm, marked “D / 800”

    PackageNDC
    Bottle of 3059651-086-30

    Inactive ingredients: silicon dioxide, crospovidone (35 .mu.m), hydroxypropyl cellulose (110000 wamw), polyethylene glycol 3350, magnesium stearate, microcrystalline cellulose 101, polyvinyl alcohol, talc, titanium dioxide, FD&C Yellow No. 6, ferric oxide red

    FDA label

  • Camber Pharmaceuticals600 mg, 800 mg

    Has a dye: FD&C Yellow No. 6 · Made by Annora Pharma and Hetero Labs

    Product page on camberpharma.com

    How it looks, what’s in it, NDCs

    600 mg Orange, oval, 21 mm, marked “J / 7”

    PackageNDC
    Bottle of 6031722-568-60

    800 mg Yellow, oval, 20 mm, marked “V / 7”

    PackageNDC
    Bottle of 3031722-089-30

    Inactive ingredients: silicon dioxide, crospovidone (35 .mu.m), magnesium stearate, microcrystalline cellulose, FD&C Yellow No. 6, polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide, silicified microcrystalline cellulose (125 .micro.m, high-density), ferric oxide yellow

    FDA label

  • Cipla600 mg, 800 mg

    Has a dye: FD&C Yellow No. 6

    How it looks, what’s in it, NDCs

    600 mg BEIGE, capsule, 21 mm, marked “C248”

    PackageNDC
    Bottle of 6069097-248-03

    800 mg WHITE TO OFF-WHITE, capsule, 21 mm, marked “C244”

    PackageNDC
    Bottle of 3069097-244-02

    Inactive ingredients: cellulose, microcrystalline, crospovidone (15 mpa.s at 5%), silicon dioxide, magnesium stearate, FD&C Yellow No. 6, polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • Dr. Reddy’s Laboratories600 mg, 800 mg

    Has dyes: FD&C Blue No. 1, FD&C Blue No. 2, FD&C Red No. 40

    How it looks, what’s in it, NDCs

    600 mg White, oval, 19 mm, marked “DA600”

    PackageNDC
    Bottle of 6043598-704-60
    Bottle of 50043598-704-05

    800 mg Blue, oval, 20 mm, marked “DA800”

    PackageNDC
    Bottle of 3043598-705-30
    Bottle of 50043598-705-05

    Inactive ingredients: silicon dioxide, croscarmellose sodium, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide, FD&C Blue No. 1, FD&C Blue No. 2, FD&C Red No. 40, aluminum oxide

    FDA label

  • Exelan Pharmaceuticals600 mg, 800 mg

    Has a dye: FD&C Yellow No. 6 · Made by Cipla

    How it looks, what’s in it, NDCs

    600 mg BEIGE, capsule, 21 mm, marked “C248”

    PackageNDC
    Bottle of 6076282-737-60

    800 mg WHITE TO OFF-WHITE, capsule, 21 mm, marked “C244”

    PackageNDC
    Bottle of 3076282-738-30

    Inactive ingredients: cellulose, microcrystalline, crospovidone (15 mpa.s at 5%), silicon dioxide, magnesium stearate, FD&C Yellow No. 6, polyethylene glycol 3350, polyvinyl alcohol, talc, titanium dioxide

    FDA label

  • Lupin Pharmaceuticals600 mg, 800 mg

    Has a dye: FD&C Yellow No. 6

    How it looks, what’s in it, NDCs

    600 mg Orange, oval, 21 mm, marked “LU / A42”

    PackageNDC
    Bottle of 6068180-345-07

    800 mg Dark Red, oval, 19 mm, marked “LU / A46”

    PackageNDC
    Bottle of 3068180-346-06

    Inactive ingredients: cellulose, microcrystalline, crospovidone (120 .mu.m), FD&C Yellow No. 6, magnesium stearate, polyethylene glycol 3350, polyvinyl alcohol, silicon dioxide, talc, titanium dioxide, ferric oxide red, hypromellose 2910 (5 mpa.s)

    FDA label

  • Novadoz Pharmaceuticals600 mg, 800 mg

    Made by MSN Laboratories

    Product page on novadozpharma.com

    How it looks, what’s in it, NDCs

    600 mg Beige, oval, 19 mm, marked “M / 600”

    PackageNDC
    Bottle of 6072205-184-60

    800 mg Brown, oval, 20 mm, marked “M / 800”

    PackageNDC
    Bottle of 3072205-185-30

    Inactive ingredients: silicon dioxide, crospovidone, hydroxypropyl cellulose, magnesium stearate, polacrilin potassium, microcrystalline cellulose, sodium chloride, polyvinyl alcohol, ferric oxide yellow, ferric oxide red, polyethylene glycol 3350, talc, titanium dioxide

    FDA label

  • Viona Pharmaceuticals600 mg, 800 mg

    Made by Zydus Lifesciences

    Product page on vionausa.com

    How it looks, what’s in it, NDCs

    600 mg Brown, oval, 20 mm, marked “1215”

    PackageNDC
    Bottle of 6072578-147-14
    Bottle of 18072578-147-28
    Bottle of 50072578-147-05

    800 mg Beige colored, oval, 21 mm, marked “1217”

    PackageNDC
    Bottle of 3072578-148-06
    Bottle of 9072578-148-16
    Bottle of 50072578-148-05

    Inactive ingredients: ferric oxide red, ferric oxide yellow, ferrosoferric oxide, hydroxypropyl cellulose, hypromellose 2910 (6 mpa.s), magnesium stearate, microcrystalline cellulose, silicon dioxide, sodium starch glycolate type a potato, talc, titanium dioxide

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Prezista, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

PREZISTA is a human immunodeficiency virus (HIV-1) protease inhibitor indicated for the treatment of HIV-1 infection in adult and pediatric patients 3 years of age and older. PREZISTA must be co-administered with ritonavir (PREZISTA/ritonavir) and with other antiretroviral agents.

Source: the FDA label for Prezista (Janssen Products LP), August 29, 2025. Full label on DailyMed 

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