Prilosec

Generic name: omeprazole

Used for: Heartburn and acid reflux (GERD) · Erosive esophagitis from acid reflux (GERD) · Stomach and intestinal ulcers (gastric and duodenal) · H. pylori infection and ulcers · Too much stomach acid (hypersecretory conditions) · 4 more

How do you pay?

How to pay the least

Ask for the cash price

Prilosec

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

  1. Ask your pharmacy for Prilosec’s cash price, and one or two other pharmacies too.

Compare every option

Question
Brand namePrilosec
Authorized genericomeprazole
Regular genericomeprazole
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Other forms onlyAsk your doctor
Same as Prilosec?
The original
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Brand nameWith a free discount coupon

Optum Perks, Optum’s free discount coupon, lists these prices for Prilosec without insurance. Show the coupon from its page at the pharmacy; it can’t be used with insurance.

From Optum Perks, read November 2, 2026, with no location set. Its page opens on this dose; other doses and pharmacies near you are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold

There isn’t one. An authorized generic is Prilosec itself, from the same company, sold without the brand name, and usually for less. For now Prilosec is the only choice; ask the pharmacy for its cash price, or your plan what it charges.

See the brand name →

Regular genericNot sold

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you. Generics usually come once the brand’s patents and exclusivity end. Until then, ask the pharmacy for Prilosec’s cash price, or your plan what it charges.

See the brand name →

What it’s used for

What the FDA label says

PRILOSEC is a proton pump inhibitor (PPI) indicated for the:

  • Treatment of active duodenal ulcer in adults
  • Eradication of Helicobacter pylori to reduce the risk of duodenal ulcer recurrence in adults
  • Treatment of active benign gastric ulcer in adults
  • Treatment of symptomatic gastroesophageal reflux disease (GERD) in patients 1 year of age and older
  • Treatment of erosive esophagitis (EE) due to acid-mediated GERD in patients 1 month of age and older
  • Maintenance of healing of EE due to acid-mediated GERD in patients 1 year of age and older
  • Pathologic hypersecretory conditions in adults

Source: the FDA label for Prilosec (Covis Pharma US, Inc), March 19, 2024. Full label on DailyMed 

Good to know

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/prilosec/