How do you pay?

How to pay the least

From

$12.77 for 30 capsules delivered ($7.52 plus $5.25 shipping)

Generic tacrolimus from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic tacrolimus. It comes by mail.

Need it today? From $15.41 for 30 capsules with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card 

With a membership From $9.16 for 30 capsules from Amazon Pharmacy, by mail ($139 a year).

Open Amazon Pharmacy 

A regular generic has the same active ingredient as Prograf, and the FDA requires it to work the same way.

Compare every option

Question
Brand namePrograf
Authorized generictacrolimus
Regular generictacrolimus
What you’d pay
At least$100for 30 capsules; pharmacies pay this
Not soldThere isn’t one
From$12.77for 30 capsules at Cost Plus Drugs, with shipping
Same as Prograf?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Astellas Copay Card Program

Savings card from Astellas

No insuranceNeeds insuranceNo cash price listed.
Insurance · up to $3,000 off a year

The card takes up to $3,000 a year off your co-pay.

Sign up on astellascares.com 

In the maker’s words

“Eligible participants in the Copay Card Program ("Program") may receive annual savings up to $3000 for PROGRAF or ASTAGRAF XL.”

From the maker’s offer on astellascares.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Prograf itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic tacrolimus, lowest first.

Pick up in storeDelivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

12 companies sell a generic of Prograf that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Ascend LaboratoriesCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Made by Alkem Laboratories

    How it looks, what’s in it, NDCs

    0.5 mg Yellow, capsule, 11 mm, marked “0 / 5mg / Tacro”

    PackageNDC
    Carton of 5067877-278-33
    Bottle of 10067877-278-01

    1 mg White, capsule, 11 mm, marked “1mg / Tacro”

    PackageNDC
    Carton of 5067877-279-33
    Bottle of 10067877-279-01

    5 mg Red, capsule, 14 mm, marked “5mg / Tacro”

    PackageNDC
    Carton of 5067877-280-33
    Bottle of 10067877-280-01

    Inactive ingredients: anhydrous lactose, hypromellose 2910 (6 mpa.s), croscarmellose sodium, magnesium stearate, ferric oxide yellow, titanium dioxide, gelatin, sodium lauryl sulfate, ferric oxide red

    FDA label

  • Biocon PharmaCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Has a dye: FD&C Red No. 40

    How it looks, what’s in it, NDCs

    0.5 mg Light Yellow, capsule, 14 mm, marked “Biocon / logo / T / 0 / 5”

    PackageNDC
    Bottle of 10070377-014-11

    1 mg White, capsule, 14 mm, marked “Bioconlogo / T / 1”

    PackageNDC
    Bottle of 10070377-015-11

    5 mg Greyish red, capsule, 14 mm, marked “Biocon / logo / T / 5”

    PackageNDC
    Bottle of 10070377-016-11

    Inactive ingredients: anhydrous lactose, hypromellose 2910 (6 mpa.s), croscarmellose sodium, magnesium stearate, gelatin, titanium dioxide, ferric oxide yellow, shellac, propylene glycol, sodium hydroxide, povidone, FD&C Red No. 40, ferric oxide red, ammonia, potassium hydroxide

  • Dr. Reddy’s LaboratoriesCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose

    How it looks, what’s in it, NDCs

    0.5 mg Dark yellow, capsule, 14 mm, marked “0 / 5MG / RDY525”

    PackageNDC
    Carton of 3055111-525-30
    Carton of 10055111-525-01
    Carton of 10055111-525-78
    Carton of 50055111-525-05

    1 mg White, capsule, 14 mm, marked “1MG / RDY526”

    PackageNDC
    Carton of 3055111-526-30
    Carton of 10055111-526-01
    Carton of 10055111-526-78
    Carton of 50055111-526-05

    5 mg Dark grayish red, capsule, 14 mm, marked “5MG / RDY527”

    PackageNDC
    Carton of 3055111-527-30
    Carton of 10055111-527-01
    Carton of 10055111-527-78
    Carton of 50055111-527-05

    Inactive ingredients: croscarmellose sodium, lactose monohydrate, magnesium stearate, gelatin, ferric oxide red, ferric oxide yellow, titanium dioxide, ferrosoferric oxide

    FDA label

  • Glenmark PharmaceuticalsCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Has dyes: D&C Yellow No. 10, FD&C Blue No. 1, FD&C Red No. 40

    Product page on glenmarkpharma-us.com

    How it looks, what’s in it, NDCs

    0.5 mg Light yellow cap and light yellow body, capsule, 14 mm, marked “G / 685”

    PackageNDC
    Bottle of 10068462-685-01

    1 mg White cap and white body, capsule, 14 mm, marked “G / 686”

    PackageNDC
    Bottle of 10068462-686-01
    Carton of 10068462-686-14

    5 mg Greyish red cap and greyish red body, capsule, 14 mm, marked “G / 687”

    PackageNDC
    Bottle of 10068462-687-01
    Carton of 10068462-687-14

    Inactive ingredients: hypromellose, croscarmellose sodium, lactose monohydrate, magnesium stearate, gelatin, FD&C Blue No. 1, FD&C Red No. 40, D&C Yellow No. 10, titanium dioxide, shellac, sodium hydroxide, povidone, potassium hydroxide

    FDA label

  • Jubilant CadistaCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Made by Panacea Biotec

    Product page on cadista.com

    How it looks, what’s in it, NDCs

    0.5 mg Yellow, capsule, 5 mm, marked “PBT / 0 / 5”

    PackageNDC
    Bottle of 10059746-798-01

    1 mg White, capsule, 5 mm, marked “PBT / 1 / 0”

    PackageNDC
    Bottle of 10059746-799-01

    5 mg Pink, capsule, 4 mm, marked “PBT / 5 / 0”

    PackageNDC
    Bottle of 10059746-800-01

    Inactive ingredients: anhydrous lactose, hypromellose 2910 (5 mpa.s), hypromellose 2910 (15 mpa.s), croscarmellose sodium, magnesium stearate, gelatin, titanium dioxide, ferric oxide yellow

    FDA label

  • Mylan InstitutionalCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Has dyes: D&C Red No. 28, D&C Yellow No. 10, FD&C Blue No. 1, FD&C Blue No. 2, FD&C Red No. 40, FD&C Red No. 3, D&C Red No. 33

    How it looks, what’s in it, NDCs

    0.5 mg Light orange opaque and gray opaque, capsule, 14 mm, marked “MYLAN / 2045”

    PackageNDC
    Carton of 10051079-817-20

    1 mg Light blue opaque and gray opaque, capsule, 14 mm, marked “MYLAN / 2046”

    PackageNDC
    Carton of 10051079-818-20

    5 mg Rubine red opaque and gray opaque, capsule, 14 mm, marked “MYLAN / 2047”

    PackageNDC
    Carton of 10051079-028-20

    Inactive ingredients: anhydrous lactose, ferrosoferric oxide, silicon dioxide, croscarmellose sodium, gelatin, hypromellose, lactose monohydrate, magnesium stearate, sodium lauryl sulfate, titanium dioxide, ferric oxide yellow, D&C Red No. 28, D&C Yellow No. 10, FD&C Red No. 40, FD&C Blue No. 1, FD&C Blue No. 2, propylene glycol, shellac, FD&C Red No. 3, D&C Red No. 33

    FDA label

  • Mylan PharmaceuticalsCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Has dyes: D&C Red No. 28, D&C Yellow No. 10, FD&C Blue No. 1, FD&C Blue No. 2, FD&C Red No. 40, FD&C Red No. 3, D&C Red No. 33

    Product page on viatris.com

    How it looks, what’s in it, NDCs

    0.5 mg Light orange opaque and gray opaque, capsule, 14 mm, marked “MYLAN / 2045”

    PackageNDC
    Bottle of 1000378-2045-01

    1 mg Light blue opaque and gray opaque, capsule, 14 mm, marked “MYLAN / 2046”

    PackageNDC
    Bottle of 1000378-2046-01

    5 mg Rubine red opaque and gray opaque, capsule, 14 mm, marked “MYLAN / 2047”

    PackageNDC
    Bottle of 1000378-2047-01

    Inactive ingredients: anhydrous lactose, ferrosoferric oxide, silicon dioxide, croscarmellose sodium, gelatin, hypromellose, lactose monohydrate, magnesium stearate, sodium lauryl sulfate, titanium dioxide, ferric oxide yellow, D&C Red No. 28, D&C Yellow No. 10, FD&C Red No. 40, FD&C Blue No. 1, FD&C Blue No. 2, propylene glycol, shellac, FD&C Red No. 3, D&C Red No. 33

    FDA label

  • Nexus PharmaceuticalsInjection 5 mg/mL

    Product page on nexuspharma.net

    How it looks, what’s in it, NDCs

    5 mg/mL

    PackageNDC
    Carton of 10 mL14789-135-05

    Inactive ingredients: peg-60 hydrogenated castor oil, alcohol

    FDA label

  • NorthStar RxCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Has dyes: D&C Yellow No. 10, FD&C Blue No. 1, FD&C Red No. 40 · Made by Glenmark Pharmaceuticals

    Product page on northstarrxllc.com

    How it looks, what’s in it, NDCs

    0.5 mg Light yellow cap and light yellow body, capsule, 14 mm, marked “G / 685”

    PackageNDC
    Bottle of 10016714-098-01

    1 mg White cap and white body, capsule, 14 mm, marked “G / 686”

    PackageNDC
    Bottle of 10016714-099-01

    5 mg Greyish red cap and greyish red body, capsule, 14 mm, marked “G / 687”

    PackageNDC
    Bottle of 10016714-100-01

    Inactive ingredients: hypromellose, croscarmellose sodium, lactose monohydrate, magnesium stearate, gelatin, FD&C Blue No. 1, FD&C Red No. 40, D&C Yellow No. 10, titanium dioxide, shellac, sodium hydroxide, povidone, potassium hydroxide

    FDA label

  • SandozCapsule 0.5 mg, 1 mg, 5 mg

    Product page on sandoz.com

    Packages and NDCs

    0.5 mg

    PackageNDC
    Bottle of 1000781-2102-01

    1 mg

    PackageNDC
    Bottle of 1000781-2103-01

    5 mg

    PackageNDC
    Bottle of 1000781-2104-01
  • Stellon BiotechCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Made by Concord Biotech

    How it looks, what’s in it, NDCs

    0.5 mg Opaque light, capsule, 14 mm, marked “C5 / 05mg”

    PackageNDC
    Bottle of 3085972-101-30
    Bottle of 10085972-101-01

    1 mg Opaque, capsule, 14 mm, marked “C6 / 1mg”

    PackageNDC
    Bottle of 3085972-102-30
    Bottle of 10085972-102-01

    5 mg Opaque Grayish, capsule, 14 mm, marked “C7 / 5mg”

    PackageNDC
    Bottle of 3085972-103-30
    Bottle of 10085972-103-01

    Inactive ingredients: anhydrous lactose, croscarmellose sodium, hypromellose 2910 (15 mpa.s), magnesium stearate, ferric oxide yellow, gelatin, titanium dioxide, shellac, propylene glycol, ammonia, ferrosoferric oxide, potassium hydroxide, ferric oxide red

    FDA label

  • Strides Pharma ScienceCapsule 0.5 mg, 1 mg, 5 mg

    Has lactose · Has dyes: FD&C Blue No. 1, FD&C Red No. 40, D&C Red No. 28, D&C Yellow No. 10

    How it looks, what’s in it, NDCs

    0.5 mg Red opaque cap and red opaque body, capsule, 11 mm, marked “SAL / 720”

    PackageNDC
    Carton of 10064380-720-01
    Container of 10064380-720-06

    1 mg Green opaque cap and green opaque body, capsule, 11 mm, marked “SAL / 721”

    PackageNDC
    Carton of 10064380-721-01
    Container of 10064380-721-06

    5 mg Teal opaque cap and teal opaque body, capsule, 14 mm, marked “SAL / 722”

    PackageNDC
    Carton of 10064380-722-01
    Container of 10064380-722-06

    Inactive ingredients: croscarmellose sodium, FD&C Blue No. 1, FD&C Red No. 40, gelatin, hypromellose 2910 (5 mpa.s), lactose monohydrate, magnesium stearate, titanium dioxide, ferric oxide yellow, D&C Red No. 28, D&C Yellow No. 10

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Prograf, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

PROGRAF is a calcineurin-inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in adult and pediatric patients receiving allogeneic liver, kidney, heart, or lung transplants, in combination with other immunosuppressants.

Source: the FDA label for Prograf (Astellas Pharma US, Inc.), August 25, 2023. Full label on DailyMed 

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