Brand-name prescription

Prograf

tacrolimus

Compare your options

Compare	PrografBrand name	Authorized genericWithout the Prograf name	Regular generictacrolimus
What pharmacies pay	from$3.66–7.33per capsule	Not sold	Lowestfrom$0.12–0.69per capsule
Same as Prograf?	The original	–	Same active ingredientFillers and dyes can differ
Ways to save	Maker’s cardup to $3,000 off a yearwith commercial insurance	–	Ask for it by name
With insurance	Brand co-pay, usually the highest	–	Usually the lowest co-pay

No authorized generic: There isn’t one.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Astellas

Astellas Copay Card Program

With commercial insurance

up to $3,000 off a year

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

The card pays up to $3,000 a year.

Get it on astellascares.com

In the maker’s words

“Eligible participants in the Copay Card Program ("Program") may receive annual savings up to $3000 for PROGRAF or ASTAGRAF XL.”

From the maker’s offer on astellascares.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Prograf’s own card may bring it to up to $3,000 off a year.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Prograf	Regular generic
0.5 mg capsuleper capsule	$3.66	$0.12
1 mg capsuleper capsule	$7.33	$0.15
5 mg capsuleper capsule	–	$0.69
0.2 mg granule packeteach	$5.02	–
1 mg granule packeteach	$7.44	–

Good to know

A regular generic has the same active ingredient, strength and form as Prograf, and the FDA requires it to work the same way. Its fillers and dyes can differ, so it may look different.
There’s no authorized generic of Prograf.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.