How do you pay?

How to pay the least

Ask for the cash price

Prolia

Prolia is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Prolia’s cash price, and one or two other pharmacies too.
  2. Prolia’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Amgen Safety Net Foundation. Amgen Safety Net Foundation income requirements are based on a percentage of the Federal Poverty Level, adjusted for household size. Or call 1-800-932-3060.

See if you qualify 

Compare every option

Question
Brand nameProlia
Authorized genericdenosumab
Regular genericdenosumab
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone sold yet
Same as Prolia?
The original
–
–

Brand nameThe maker’s card

Amgen SupportPlus Co-Pay Program

Savings card from Amgen

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a dose

Sign up on prolia.com 

In the maker’s words

“For Prolia®, you may pay as little as $0 out-of-pocket for each dose.”

From the maker’s offer on prolia.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Prolia itself, from the same company, sold without the brand name, and usually for less. For now Prolia is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Prolia is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

Prolia is a RANK ligand (RANKL) inhibitor indicated for treatment:

  • of postmenopausal women with osteoporosis at high risk for fracture
  • to increase bone mass in men with osteoporosis at high risk for fracture
  • of glucocorticoid-induced osteoporosis in men and women at high risk for fracture
  • to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for nonmetastatic prostate cancer
  • to increase bone mass in women at high risk for fracture receiving adjuvant aromatase inhibitor therapy for breast cancer

Source: the FDA label for Prolia (Amgen, Inc), June 26, 2026. Full label on DailyMed 

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