How do you pay?

How to pay the least

From

$14.70 for 30 capsules delivered ($9.45 plus $5.25 shipping)

Generic progesterone from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic progesterone. It comes by mail.

Need it today? From $19.50 for 30 capsules with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card 

A regular generic has the same active ingredient as Prometrium, and the FDA requires it to work the same way.

Compare every option

Question
Brand namePrometrium
Authorized genericprogesterone
Regular genericprogesterone
What you’d pay
At least$470for 30 capsules; pharmacies pay this
Not soldThere isn’t one
From$14.70for 30 capsules at Cost Plus Drugs, with shipping
Same as Prometrium?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Prometrium’s maker. Ask the pharmacy for Prometrium’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Prometrium itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic progesterone, lowest first.

Pick up in storeDelivered

From each pharmacy’s and clinic’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less. Most online clinics don’t take insurance.

Regular genericWho makes it

6 companies sell a generic of Prometrium that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Amneal PharmaceuticalsAll 2 strengths

    Has dyes: D&C Yellow No. 10, FD&C Yellow No. 6

    How it looks, what’s in it, NDCs

    100 mg Light orange, round, 8 mm, marked “A87”

    PackageNDC
    Bottle of 10065162-807-10
    Bottle of 50065162-807-50

    200 mg Light orange, oval, 15 mm, marked “A80”

    PackageNDC
    Bottle of 10065162-808-10
    Bottle of 50065162-808-50

    Inactive ingredients: lecithin, soybean, gelatin, glycerin, titanium dioxide, water, D&C Yellow No. 10, FD&C Yellow No. 6, peanut oil

    FDA label

  • Aurobindo PharmaAll 2 strengths

    Made by Eugia Pharma Specialities

    Product page on aurobindousa.com

    How it looks, what’s in it, NDCs

    100 mg White to off white, round, 8 mm, marked “P1”

    PackageNDC
    Bottle of 10059651-152-01

    200 mg White to off white, oval, 15 mm, marked “P2”

    PackageNDC
    Bottle of 10059651-153-01

    Inactive ingredients: gelatin type b bovine (160 bloom), glycerin, hypromellose 2910 (6 mpa.s), ferrosoferric oxide, lecithin, soybean, peanut oil, propylene glycol, titanium dioxide

    FDA label

  • BionpharmaAll 2 strengths

    Product page on bionpharma.com

    How it looks, what’s in it, NDCs

    100 mg Orange, oval, 13 mm, marked “P / 1”

    PackageNDC
    Bottle of 10069452-148-20

    100 mg Yellow, oval, 13 mm, marked “P / 3”

    PackageNDC
    Bottle of 10069452-233-20

    200 mg Red, oval, 15 mm, marked “P / 2”

    PackageNDC
    Bottle of 10069452-149-20

    200 mg White, oval, 15 mm, marked “P / 4”

    PackageNDC
    Bottle of 10069452-234-20

    Inactive ingredients: ferric oxide red, ferric oxide yellow, gelatin, glycerin, lecithin, soybean, peanut oil, titanium dioxide

    FDA label

  • Hikma PharmaceuticalsAll 2 strengths

    Has dyes: D&C Yellow No. 10, FD&C Red No. 40 · Made by Sofgen Pharmaceuticals

    How it looks, what’s in it, NDCs

    100 mg Pink, round, 9 mm, marked “100”

    PackageNDC
    Bottle of 1000054-0829-25

    200 mg Beige, oval, 14 mm, marked “200”

    PackageNDC
    Bottle of 1000054-0830-25

    Inactive ingredients: peanut oil, gelatin, glycerin, lecithin, soybean, titanium dioxide, D&C Yellow No. 10, FD&C Red No. 40

    FDA label

  • NorthStar RxAll 2 strengths

    Made by Xiromed Pharma Espana SL

    Product page on northstarrxllc.com

    How it looks, what’s in it, NDCs

    100 mg Off-White, oval, 12 mm, marked “PR1”

    PackageNDC
    Bottle of 10016714-157-01

    200 mg Off-White, oval, 16 mm, marked “PR2”

    PackageNDC
    Bottle of 10016714-158-01

    Inactive ingredients: peanut oil, gelatin, glycerin, lecithin, soybean, titanium dioxide, medium-chain triglycerides

    FDA label

  • XiromedAll 2 strengths

    Product page on xiromed.com

    How it looks, what’s in it, NDCs

    100 mg Off-White, oval, 12 mm, marked “PR1”

    PackageNDC
    Bottle of 10070700-162-01

    200 mg Off-White, oval, 16 mm, marked “PR2”

    PackageNDC
    Bottle of 10070700-163-01

    Inactive ingredients: peanut oil, gelatin, glycerin, lecithin, soybean, titanium dioxide, medium-chain triglycerides

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Prometrium, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

PROMETRIUM® (progesterone, USP) Capsules are indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also indicated for use in secondary amenorrhea.

Source: the FDA label for Prometrium (Acertis Pharmaceuticals, LLC), July 23, 2026. Full label on DailyMed 

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