How do you pay?

How to pay the least

Ask for the cash price

Pulmozyme

Pulmozyme is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Pulmozyme’s cash price, and one or two other pharmacies too.
  2. Pulmozyme’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Genentech Patient Foundation. Do not have insurance coverage for their Genentech medicine and their household makes less than $150,000 per year Or call (888) 941-3331.

See if you qualify 

Compare every option

Question
Brand namePulmozyme
Authorized genericdornase alfa
Regular genericdornase alfa
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone sold yet
Same as Pulmozyme?
The original
–
–

Brand nameThe maker’s card

Pulmozyme Co-pay Program

Savings card from Genentech

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $30 a month

The card takes up to $10,000 a year off your co-pay.

Sign up on pulmozyme.com 

Or call 1-866-422-2377.

In the maker’s words

“The Pulmozyme Co-pay Program works to help eligible, commercially insured patients pay as little as $30 for a 30-day supply of Pulmozyme.”

From the maker’s offer on pulmozyme.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Pulmozyme itself, from the same company, sold without the brand name, and usually for less. For now Pulmozyme is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Pulmozyme is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

PULMOZYME is a recombinant DNase enzyme indicated in conjunction with standard therapies for the management of cystic fibrosis (CF) patients to improve pulmonary function.

Source: the FDA label for Pulmozyme (Genentech, Inc.), December 17, 2025. Full label on DailyMed 

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