Rapamune

Generic name: sirolimus

Used for: Preventing kidney transplant rejection · Lymphangioleiomyomatosis (LAM), a rare lung disease · 1 more

How do you pay?

How to pay the least

From

$27.49 for 30 tablets delivered ($22.24 plus $5.25 shipping)

Generic sirolimus from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic sirolimus. It comes by mail.

Need it today? From $28.58 for 30 tablets with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card 

A regular generic has the same active ingredient as Rapamune, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameRapamune
Authorized genericsirolimus
Regular genericsirolimus
What you’d pay
Not soldNo longer sold
Cash priceAsk the pharmacyUsually among the lowest
From$27.49for 30 tablets at Cost Plus Drugs, with shipping
Same as Rapamune?
–
Same medicine
Same active ingredientFillers and dyes can differ

Brand nameNot sold

Rapamune itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the authorized generic →

Authorized genericThe NDC to ask for

The same medicine as Rapamune, without the brand name. Give the pharmacy its NDC to get it.

sirolimus

Sold by
  • Mylan Pharmaceuticals
Your strength
NDC to ask for
  • 0.5 mgsugar-coated tablet
    • 59762-1001-111-digit: 59762-1001-01100 tablets per bottle
  • 1 mg/mLsolution
    • 59762-1205-611-digit: 59762-1205-0660 mL per bottle
  • 1 mgsugar-coated tablet
    • 59762-1002-111-digit: 59762-1002-01100 tablets per bottle
  • 2 mgsugar-coated tablet
    • 59762-1003-111-digit: 59762-1003-01100 tablets per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Rapamune, can you tell me what I’d pay for the brand, for the authorized generic from Mylan Pharmaceuticals, and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

0.5 mg sugar-coated tablet

Rapamune itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized genericMylan Pharmaceuticals
See the ingredients

Active: sirolimus 0.5 mg

Inactive:

  • Alpha-tocopherol acetate
  • Calcium sulfate
  • Carnauba wax
  • Ferric oxide yellow
  • Glyceryl oleate
  • Lactose monohydrate
  • Magnesium stearate
  • Microcrystalline cellulose
  • Poloxamer 188
  • Polyethylene glycol 8000
  • Povidone k30
  • Sucrose
  • Talc
  • Titanium dioxide

1 mg sugar-coated tablet

Rapamune itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized genericMylan Pharmaceuticals
See the ingredients

Active: sirolimus 1 mg

Inactive:

  • Alpha-tocopherol acetate
  • Calcium sulfate
  • Carnauba wax
  • Glyceryl oleate
  • Lactose monohydrate
  • Magnesium stearate
  • Microcrystalline cellulose
  • Poloxamer 188
  • Polyethylene glycol 8000
  • Povidone k30
  • Sucrose
  • Talc
  • Titanium dioxide

2 mg sugar-coated tablet

Rapamune itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized genericMylan Pharmaceuticals
See the ingredients

Active: sirolimus 2 mg

Inactive:

  • Alpha-tocopherol acetate
  • Calcium sulfate
  • Carnauba wax
  • Glyceryl oleate
  • Lactose monohydrate
  • Magnesium stearate
  • Microcrystalline cellulose
  • Poloxamer 188
  • Polyethylene glycol 8000
  • Povidone k30
  • Sucrose
  • Talc
  • Titanium dioxide

1 mg/mL solution

Rapamune itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized genericMylan Pharmaceuticals
See the ingredients

Active: sirolimus 1 mg/mL

Inactive:

  • Alcohol
  • Ascorbyl palmitate
  • Glyceryl mono- and dipalmitostearate
  • Polysorbate 80
  • Propylene glycol
  • Soy acid
  • Soybean phosphatidylcholine

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic sirolimus, lowest first.

Pick up in storeDelivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

11 companies sell a generic of Rapamune that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Amneal PharmaceuticalsSolution 1 mg/mL
    How it looks, what’s in it, NDCs

    1 mg/mL A clear, yellow colored solution

    PackageNDC
    Kit of 60 mL69238-1594-3

    Inactive ingredients: alcohol, ascorbyl palmitate, propylene glycol, soy acid, sunflower seed oil glycereth-8 esters, tocopherol, polysorbate 80, nitrogen, phosphatidylcholine, soybean

    FDA label

  • ApotexSolution 1 mg/mL
    Packages and NDCs

    1 mg/mL

    PackageNDC
    Carton of 60 mL60505-6197-2
  • Ascend LaboratoriesTablet 0.5 mg, 1 mg, 2 mg

    Has lactose · Has dyes: D&C Yellow No. 10, FD&C Yellow No. 6 · Made by Alkem Laboratories

    How it looks, what’s in it, NDCs

    0.5 mg TAN, round, 4 mm, marked “S”

    PackageNDC
    Bottle of 3067877-746-30
    Bottle of 10067877-746-01
    Bottle of 50067877-746-05
    Carton of 100067877-746-38

    1 mg White, round, 6 mm, marked “S / 1”

    PackageNDC
    Bottle of 3067877-747-30
    Bottle of 10067877-747-01
    Bottle of 50067877-747-05
    Carton of 100067877-747-38

    2 mg Yellow, round, 7 mm, marked “S / 2”

    PackageNDC
    Bottle of 3067877-748-30
    Bottle of 10067877-748-01
    Bottle of 50067877-748-05
    Carton of 100067877-748-38

    Inactive ingredients: edetate disodium, poloxamer 188, hypromellose 2910 (5 mpa.s), sucrose, .alpha.-tocopherol, dl-, microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, glyceryl dibehenate, polyethylene glycol, polyvinyl alcohol, titanium dioxide, glyceryl monocaprylocaprate, sodium lauryl sulfate, ferric oxide yellow, ferrosoferric oxide, ferric oxide red, talc, FD&C Yellow No. 6, D&C Yellow No. 10

    FDA label

  • Camber PharmaceuticalsSolution 1 mg/mL

    Made by Hetero Labs

    Product page on camberpharma.com

    How it looks, what’s in it, NDCs

    1 mg/mL Pale yellow to yellow

    PackageNDC
    Kit of 60 mL31722-316-31

    Inactive ingredients: polysorbate 80, alcohol, ascorbyl palmitate, soybean phosphatidylcholine, propylene glycol, soy acid, sunflower oil mono/diglycerides, tocopherol

    FDA label

  • Dr. Reddy’s LaboratoriesTablet 1 mg, 2 mg

    Has lactose · Has a dye: FD&C Red No. 40

    How it looks, what’s in it, NDCs

    1 mg White, triangle, 5 mm, marked “RD53”

    PackageNDC
    Bottle of 3055111-653-30
    Bottle of 10055111-653-01

    2 mg Creamish yellow, triangle, 5 mm, marked “RD54”

    PackageNDC
    Bottle of 3055111-654-30
    Bottle of 10055111-654-01

    Inactive ingredients: carnauba wax, ethylcelluloses, hypromellose 2910 (5 mpa.s), lactose monohydrate, magnesium stearate, mannitol, poloxamer 188, cellulose, microcrystalline, polyethylene glycol, sucrose, titanium dioxide, alpha-tocopherol, povidone, shellac, ammonia, FD&C Red No. 40, propylene glycol, ferric oxide red, ferric oxide yellow

    FDA label

  • Glenmark PharmaceuticalsTablet 0.5 mg, 1 mg, 2 mg

    Has lactose · Has dyes: D&C Yellow No. 10, FD&C Blue No. 2, FD&C Yellow No. 6

    Product page on glenmarkpharma-us.com

    How it looks, what’s in it, NDCs

    0.5 mg Gray to greenish-gray, round, 4 mm, marked “Y / 7”

    PackageNDC
    Bottle of 10068462-682-01

    1 mg White to off-white, round, 6 mm, marked “Y / 77”

    PackageNDC
    Bottle of 10068462-683-01

    2 mg Yellow to orange-yellow, round, 7 mm, marked “Y / 71”

    PackageNDC
    Bottle of 10068462-684-01

    Inactive ingredients: croscarmellose sodium, edetate disodium, glyceryl dibehenate, hypromellose, lactose monohydrate, microcrystalline cellulose, poloxamer 188, polyethylene glycol, sucrose, titanium dioxide, .alpha.-tocopherol, dl-, ferrosoferric oxide, ferric oxide red, ferric oxide yellow, D&C Yellow No. 10, FD&C Blue No. 2, FD&C Yellow No. 6

    FDA label

  • NorthStar RxTablet 0.5 mg, 1 mg, 2 mg · Solution 1 mg/mL

    Has lactose · Has dyes: D&C Yellow No. 10, FD&C Blue No. 2, FD&C Yellow No. 6 · Made by Glenmark Pharmaceuticals and MSN Laboratories

    Product page on northstarrxllc.com

    How it looks, what’s in it, NDCs

    0.5 mg Gray to greenish-gray, round, 4 mm, marked “Y / 7”

    PackageNDC
    Bottle of 10016714-187-01

    1 mg White to off-white, round, 6 mm, marked “Y / 77”

    PackageNDC
    Bottle of 10016714-188-01

    1 mg/mL Yellow

    PackageNDC
    Carton of 60 mL72603-409-01

    2 mg Yellow to orange-yellow, round, 7 mm, marked “Y / 71”

    PackageNDC
    Bottle of 10016714-189-01

    Inactive ingredients: croscarmellose sodium, edetate disodium, glyceryl dibehenate, hypromellose, lactose monohydrate, microcrystalline cellulose, poloxamer 188, polyethylene glycol, sucrose, titanium dioxide, .alpha.-tocopherol, dl-, ferrosoferric oxide, ferric oxide red, ferric oxide yellow, polysorbate 80, soybean phosphatidylcholine, propylene glycol, sunflower oil mono/diglycerides, soy acid, alcohol, ascorbyl palmitate, tocopherol, D&C Yellow No. 10, FD&C Blue No. 2, FD&C Yellow No. 6

    FDA label

  • Novadoz PharmaceuticalsSolution 1 mg/mL

    Made by MSN Laboratories

    Product page on novadozpharma.com

    How it looks, what’s in it, NDCs

    1 mg/mL Yellow

    PackageNDC
    Carton of 60 mL72205-099-78

    Inactive ingredients: polysorbate 80, soybean phosphatidylcholine, propylene glycol, sunflower oil mono/diglycerides, soy acid, alcohol, ascorbyl palmitate, tocopherol

    FDA label

  • Rising Pharma HoldingsSolution 1 mg/mL
    How it looks, what’s in it, NDCs

    1 mg/mL

    PackageNDC
    Kit of 60 mL16571-806-06

    Inactive ingredients: propylene glycol, polysorbate 80

    FDA label

  • VistaPharmSolution 1 mg/mL

    Made by Novitium Pharma

    How it looks, what’s in it, NDCs

    1 mg/mL Yellow

    PackageNDC
    Kit of 60 mL66689-347-02

    Inactive ingredients: alcohol, ascorbyl palmitate, phosphatidylcholine, soybean, propylene glycol, soy acid, lecithin, soybean, tocopherol, polysorbate 80, sunflower oil mono/diglycerides

    FDA label

  • Zydus LifesciencesTablet 0.5 mg, 1 mg, 2 mg

    Has lactose · Has a dye: FD&C Yellow No. 5

    How it looks, what’s in it, NDCs

    0.5 mg YELLOW, round, 5 mm, marked “1”

    PackageNDC
    Bottle of 3068382-520-06
    Bottle of 9068382-520-16
    Bottle of 10068382-520-01
    Carton of 10068382-520-77
    Bottle of 50068382-520-05
    Bottle of 100068382-520-10

    1 mg WHITE TO OFF- WHITE, round, 7 mm, marked “11”

    PackageNDC
    Bottle of 10068382-351-01
    Carton of 10068382-351-77

    2 mg YELLOW, round, 9 mm, marked “21”

    PackageNDC
    Bottle of 10068382-352-01
    Carton of 10068382-352-77

    Inactive ingredients: .alpha.-tocopherol acetate, cellulose, microcrystalline, citric acid monohydrate, crospovidone, FD&C Yellow No. 5, ferric oxide yellow, glyceryl monooleate, hypromellose, lactose monohydrate, poloxamer 188, polyethylene glycol, povidone, sucrose, talc, titanium dioxide, crospovidone (120 .mu.m), hypromellose 2910 (6 mpa.s), polyethylene glycol 3350, polyethylene glycol 6000, povidone k30, ferric oxide red, ferrosoferric oxide, polyethylene glycol 8000

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

Sirolimus is an mTOR inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in patients aged ≥13 years receiving renal transplants:

  • Patients at low- to moderate-immunologic risk: Use initially with cyclosporine (CsA) and corticosteroids. CsA withdrawal is recommended 2–4 months after transplantation.
  • Patients at high-immunologic risk: Use in combination with CsA and corticosteroids for the first 12 months following transplantation. Safety and efficacy of CsA withdrawal has not been established in high risk patients.

Sirolimus is an mTOR inhibitor indicated for the treatment of patients with lymphangioleiomyomatosis.

Source: the FDA label for Sirolimus (Mylan Pharmaceuticals Inc.), March 26, 2026. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/rapamune/