How do you pay?

How to pay the least

Cash price

$1,230+ for 30 capsules

Pharmacies pay about this for Rayaldee; you’d pay more.

  1. Ask your pharmacy for Rayaldee’s cash price, and one or two other pharmacies too.
  2. Rayaldee’s savings card works only with insurance from a job or one you bought.

No generic is sold yet.

Compare every option

Question
Brand nameRayaldee
Authorized genericcalcifediol
Regular genericcalcifediol
What you’d pay
At least$1,230for 30 capsules; pharmacies pay this
Not soldThere isn’t one
Not soldNone sold yet
Same as Rayaldee?
The original
–
–

Brand nameThe maker’s card

OPKO Connect

Savings card from OPKO Pharmaceuticals

No insuranceNeeds insuranceNo cash price listed.
Insurance $0 a month

Sign up on rayaldee.com 

Or call 1-844-414-6756.

In the maker’s words

“Eligible commercially insured patients can fill their Rayaldee prescription for $0 per month.”

From the maker’s offer on rayaldee.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Rayaldee itself, from the same company, sold without the brand name, and usually for less. For now Rayaldee is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

RAYALDEE is a vitamin D3 analog indicated for the treatment of secondary hyperparathyroidism in adults with stage 3 or 4 chronic kidney disease and serum total 25-hydroxyvitamin D levels less than 30 ng/mL.

Limitations of Use:

RAYALDEE is not indicated in patients with stage 5 chronic kidney disease or end-stage renal disease on dialysis.

Source: the FDA label for Rayaldee (OPKO Pharmaceuticals LLC), January 19, 2024. Full label on DailyMed 

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