Rituxan Hycela

Generic name: rituximab and hyaluronidase

Used for: Follicular lymphoma · Diffuse large B-cell lymphoma (DLBCL) · Chronic lymphocytic leukemia (CLL) · 2 more

How do you pay?

How to pay the least

Ask for the cash price

Rituxan Hycela

Rituxan Hycela is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Rituxan Hycela’s cash price, and one or two other pharmacies too.
  2. Rituxan Hycela’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Genentech Patient Foundation. Do not have insurance coverage for their Genentech medicine and their household makes less than $150,000 per year Or call (888) 941-3331.

See if you qualify 

Compare every option

Question
Brand nameRituxan Hycela
Authorized genericrituximab and hyaluronidase
Regular genericrituximab and hyaluronidase
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Rituxan Hycela?
The original
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–

Brand nameThe maker’s card

Genentech Oncology Co-pay Assistance Program

Savings card from Genentech

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a treatment

The card takes up to $25,000 a year off your co-pay.

Sign up on rituxanhycela.com 

Or call 1-888-249-4918.

In the maker’s words

“With the Genentech Oncology Co-pay Assistance Program, eligible patients with commercial insurance could pay as little as $0 per treatment for RITUXAN HYCELA.”

From the maker’s offer on rituxanhycela.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Rituxan Hycela itself, from the same company, sold without the brand name, and usually for less. For now Rituxan Hycela is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Rituxan Hycela is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

RITUXAN HYCELA is a combination of rituximab, a CD20-directed cytolytic antibody, and hyaluronidase human, an endoglycosidase, indicated for the treatment of adult patients with:

  • Follicular Lymphoma (FL)
    • Relapsed or refractory, follicular lymphoma as a single agent
    • Previously untreated follicular lymphoma in combination with first line chemotherapy and, in patients achieving a complete or partial response to rituximab in combination with chemotherapy, as single-agent maintenance therapy
    • Non-progressing (including stable disease), follicular lymphoma as a single agent after first-line cyclophosphamide, vincristine, and prednisone (CVP) chemotherapy
  • Diffuse Large B-cell Lymphoma (DLBCL)
    • Previously untreated diffuse large B-cell lymphoma in combination with cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) or other anthracycline-based chemotherapy regimens
  • Chronic Lymphocytic Leukemia (CLL)
    • Previously untreated and previously treated CLL in combination with fludarabine and cyclophosphamide (FC)

Limitations of Use:

  • Initiate treatment with RITUXAN HYCELA only after patients have received at least one full dose of a rituximab product by intravenous infusion..
  • RITUXAN HYCELA is not indicated for the treatment of non-malignant conditions.

Source: the FDA label for Rituxan Hycela (Genentech, Inc.), September 23, 2026. Full label on DailyMed 

Good to know

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/rituxan-hycela/