Rylaze savings card: as little as $0 a prescription with commercial insurance

How to pay the least

Ask for the cash price

Rylaze

Rylaze is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Ask your pharmacy for Rylaze’s cash price, and one or two other pharmacies too.
Rylaze’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify JazzCares Patient Assistance Program (oncology). Subject to financial and residency eligibility criteria. Or call 1-833-533-5299.

See if you qualify

Compare every option

Brand nameRylaze

Authorized genericasparaginase erwinia chrysanthemi (recombinant)-rywn

Regular genericasparaginase erwinia chrysanthemi (recombinant)-rywn

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldAsk the pharmacy

Same as Rylaze?

The original

–

Brand nameThe maker’s card

RYLAZE Savings Card (JazzCares)

Savings card from Jazz Pharmaceuticals

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 a prescription

Or call 1-833-533-5299.

In the maker’s words

“If you are eligible and commercially insured, you may pay as little as $0 per prescription to help reduce your out-of-pocket costs, subject to an annual maximum…”

From the maker’s offer on jazzcares.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Rylaze itself, from the same company, sold without the brand name, and usually for less. For now Rylaze is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Rylaze is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

RYLAZE is an asparagine specific enzyme indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) in adult and pediatric patients 1 month or older who have developed hypersensitivity to E. coli-derived asparaginase.

Source: the FDA label for Rylaze (Jazz Pharmaceuticals, Inc.), July 1, 2025. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/rylaze/