Brand-name prescription

Safyral

Rx Authorized generic Available

Safyral

drospirenone, ethinyl estradiol, and levomefolate

Same medicine as Safyral, without the brand name.

Sold by

Sandoz

NDC to ask for

3 mg / 0.03 mg / 0.451 mgkit
- 0781-4103-1511-digit: 00781-4103-153 blister packs per package

Source: FDA · updated September 24, 2026

Same drug. Different label.

The official package labels and ingredient lists, from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Safyral.

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: drospirenone 3 mg · ethinyl estradiol 0.03 mg · levomefolate calcium 0.451 mg · levomefolate calcium 0.451 mg

Inactive, on both labels:

Betadex
Croscarmellose sodium
Ferric oxide red
Ferric oxide yellow
Hydroxypropyl cellulose
Hypromellose
Lactose monohydrate
Magnesium stearate
Microcrystalline cellulose
Polyethylene glycol
Talc
Titanium dioxide

What to say at the pharmacy

“Can you fill my Safyral prescription with the authorized generic from Sandoz? The NDC is 0781-4103-15. Could you check the price and whether my plan covers it?”

Good to know

It may look different from Safyral (color, shape, or markings). That’s normal for an authorized generic.
Price and coverage depend on your pharmacy and plan. Ask them to price both the brand and this NDC.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.