Septocaine

Generic name: articaine and epinephrine

Used for: Numbing for dental procedures

Septocaine is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Septocaine is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameSeptocaine
Authorized genericarticaine and epinephrine
Regular genericarticaine and epinephrine
What you’d pay
Not soldNo longer sold
Cash priceAsk the pharmacy
Not soldNone sold
Same as Septocaine?
–
Same medicine
–

Brand nameNot sold

Septocaine itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the authorized generic →

Authorized genericThe NDC to ask for

The same medicine as Septocaine, without the brand name. Give the pharmacy its NDC to get it.

articaine and epinephrine

Sold by (either works)
  • SeptodontThe company behind SeptocaineSold under the name Zorcaine
  • Benco DentalMade by Novocol Pharmaceutical of Canada, which also makes Septocaine
  • NDC, Inc.Made by Novocol Pharmaceutical of Canada, which also makes Septocaine
  • Patterson DentalMade by Novocol Pharmaceutical of Canada, which also makes Septocaine
  • Novocol Pharmaceutical of Canada
  • Dentsply PharmaceuticalSold under the name Articadent

Given by your dentist

Your dentist gives this numbing shot. It’s sold to dental offices, not pharmacies.

Your strength
NDC (for your care team)
  • 40 mg/mL / 0.01 mg/mLinjectionBenco Dental
    • 66975-417-5111-digit: 66975-0417-5150 cartridges, 1.7 mL each
  • 40 mg/mL / 0.005 mg/mLinjectionBenco Dental
    • 66975-418-5111-digit: 66975-0418-5150 cartridges, 1.7 mL each
  • 40 mg/mL / 0.01 mg/mLinjectionDentsply Pharmaceutical
    • 66312-601-1611-digit: 66312-0601-1650 cartridges, 1.7 mL each
  • 40 mg/mL / 0.005 mg/mLinjectionDentsply Pharmaceutical
    • 66312-602-1611-digit: 66312-0602-1650 cartridges, 1.7 mL each
  • 40 mg/mL / 0.01 mg/mLinjectionNDC, Inc.
    • 43128-101-0511-digit: 43128-0101-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.005 mg/mLinjectionNDC, Inc.
    • 43128-102-0511-digit: 43128-0102-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.005 mg/mLinjectionNovocol Pharmaceutical of Canada
    • 51004-0102-511-digit: 51004-0102-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.01 mg/mLinjectionNovocol Pharmaceutical of Canada
    • 51004-1010-511-digit: 51004-1010-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.01 mg/mLinjectionNovocol Pharmaceutical of Canada
    • 51004-1040-511-digit: 51004-1040-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.01 mg/mLinjectionNovocol Pharmaceutical of Canada
    • 51004-4175-111-digit: 51004-4175-0150 cartridges, 1.7 mL each
  • 40 mg/mL / 0.005 mg/mLinjectionNovocol Pharmaceutical of Canada
    • 51004-4185-111-digit: 51004-4185-0150 cartridges, 1.7 mL each
  • 40 mg/mL / 0.01 mg/mLinjectionNovocol Pharmaceutical of Canada
    • 51004-6620-511-digit: 51004-6620-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.005 mg/mLinjectionNovocol Pharmaceutical of Canada
    • 51004-6625-511-digit: 51004-6625-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.01 mg/mLinjectionPatterson Dental
    • 50227-1040-511-digit: 50227-1040-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.005 mg/mLinjectionPatterson Dental
    • 50227-1050-511-digit: 50227-1050-0550 cartridges, 1.7 mL each
  • 40 mg/mL / 0.01 mg/mLinjectionSeptodont
    • 0362-0830-0511-digit: 00362-0830-0550 cartridges, 1.7 mL each

Source: FDA, updated October 30, 2026

What to ask your dentist

“Which version of Septocaine do you use: the brand, the authorized generic? What would I pay for each?”

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

40 mg/mL / 0.01 mg/mL injection · Benco Dental

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericBenco Dental
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.01 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.005 mg/mL injection · Benco Dental

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericBenco Dental
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.005 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.01 mg/mL injection · Dentsply Pharmaceutical

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericDentsply Pharmaceutical
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.01 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.005 mg/mL injection · Dentsply Pharmaceutical

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericDentsply Pharmaceutical
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.005 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.01 mg/mL injection · NDC, Inc.

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericNDC, Inc.
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.01 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.005 mg/mL injection · NDC, Inc.

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericNDC, Inc.
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.005 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.005 mg/mL injection · Novocol Pharmaceutical of Canada

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.005 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.01 mg/mL injection · Novocol Pharmaceutical of Canada

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.01 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.01 mg/mL injection · Patterson Dental

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericPatterson Dental
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.01 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.005 mg/mL injection · Patterson Dental

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericPatterson Dental
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.005 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

40 mg/mL / 0.01 mg/mL injection · Septodont

Same active and inactive ingredients as Septocaine.

BrandSeptocaine
Authorized genericSeptodont
See the ingredients

Active: articaine hydrochloride 40 mg/mL · epinephrine bitartrate 0.01 mg/mL

Inactive, on both labels:

  • Sodium chloride
  • Sodium hydroxide
  • Sodium metabisulfite
  • Water

Regular genericNot sold

None is sold. The authorized generic is the only generic. Generics usually come once the brand’s patents and exclusivity end. Until then, the authorized generic is the lower-cost way to get Septocaine.

See the authorized generic →

What it’s used for

What the FDA label says

SEPTOCAINE is a combination of articaine HCl, an amide local anesthetic, and epinephrine, a vasoconstrictor, indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental procedures in adults and pediatric patients 4 years of age or older.

Source: the FDA label for Septocaine (Septodont Inc.), October 23, 2024. Full label on DailyMed 

Good to know

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/septocaine/