Brand-name prescription

Siklos

hydroxyurea

Compare your options

Compare	SiklosBrand name	Authorized genericWithout the Siklos name	Regular generichydroxyurea
What pharmacies pay	from$6.23–62.00per tablet	Not sold	Other forms only
Same as Siklos?	The original	–	–
Ways to save	Maker’s cardas little as $0 a prescriptionwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

Regular generic: Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Medunik

Siklos Savings Programs (Copay Card / eVoucher / Siklos at Home)

With commercial insurance

as little as $0 a prescription

Paying cash, no insurance

as little as $99 for 60 tablets

Get it on siklosusa.com

In the maker’s words

“If you have commercial insurance, there are 2 easy ways to pay as little as $0 for you or your child’s Siklos ® prescription!”

“Siklos ® 100 mg tablets: pay as little as $99 for 60 tablets or $149 for 90 tablets…”

From the maker’s offer on siklosusa.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Siklos’s own card may bring it to as little as $0 a prescription. Paying cash, the maker’s own price is as little as $99 for 60 tablets.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Siklos
1,000 mg tabletper tablet	$62.00
100 mg tabletper tablet	$6.23

Good to know

There’s no authorized generic of Siklos.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.