How do you pay?

How to pay the least

Ask for the cash price

Generic hydrocortisone

No pharmacy we check posts a price for it.

  1. Ask your pharmacy for the cash price of generic hydrocortisone.Find pharmacies near you 
  2. Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Solu-Cortef, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameSolu-Cortef
Authorized generichydrocortisone
Regular generichydrocortisone
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Not soldThere isn’t one
Cash priceAsk the pharmacyUsually the lowest
Same as Solu-Cortef?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Solu-Cortef’s maker. Ask the pharmacy for Solu-Cortef’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Solu-Cortef itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWho makes it

3 companies sell a generic of Solu-Cortef that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • ApotexPowder 100 mg/2 mL
    How it looks, what’s in it, NDCs

    100 mg/2 mL

    PackageNDC
    Carton of 2 mL60505-6411-0

    Inactive ingredients: sodium phosphate, monobasic, anhydrous, sodium phosphate, dibasic, anhydrous

    FDA label

  • CiplaInjection 100 mg/2 mL
    How it looks, what’s in it, NDCs

    100 mg/2 mL

    PackageNDC
    Carton of 2 mL69097-004-67

    Inactive ingredients: sodium phosphate, dibasic, anhydrous, sodium hydroxide, sodium phosphate, monobasic, anhydrous

    FDA label

  • Zydus LifesciencesInjection 100 mg/2 mL
    How it looks, what’s in it, NDCs

    100 mg/2 mL

    PackageNDC
    Carton of 2 mL70710-1907-1

    Inactive ingredients: sodium phosphate, dibasic, anhydrous, sodium phosphate, monobasic, anhydrous

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Solu-Cortef, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

When oral therapy is not feasible, and the strength, dosage form, and route of administration of the drug reasonably lend the preparation to the treatment of the condition, the intravenous or intramuscular use of SOLU-CORTEF Sterile Powder is indicated as follows:

Allergic states: Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, serum sickness, transfusion reactions.

Dermatologic diseases: Bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, pemphigus, severe erythema multiforme (Stevens-Johnson syndrome).

Endocrine disorders: Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance), congenital adrenal hyperplasia, hypercalcemia associated with cancer, nonsuppurative thyroiditis.

Gastrointestinal diseases: To tide the patient over a critical period of the disease in regional enteritis (systemic therapy) and ulcerative colitis.

Hematologic disorders: Acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic anemia (Diamond Blackfan anemia), idiopathic thrombocytopenic purpura in adults (intravenous administration only; intramuscular administration is contraindicated), pure red cell aplasia, select cases of secondary thrombocytopenia.

Miscellaneous: Trichinosis with neurologic or myocardial involvement, tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy.

Neoplastic diseases: For the palliative management of leukemias and lymphomas.

Nervous System: Cerebral edema associated with primary or metastatic brain tumor, or craniotomy.

Ophthalmic diseases: Sympathetic ophthalmia, uveitis and ocular inflammatory conditions unresponsive to topical corticosteroids.

Renal diseases: To induce diuresis or remission of proteinuria in idiopathic nephrotic syndrome, or that due to lupus erythematosus.

Respiratory diseases: Berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy, idiopathic eosinophilic pneumonias, symptomatic sarcoidosis.

Rheumatic disorders: As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in acute gouty arthritis; acute rheumatic carditis; ankylosing spondylitis; psoriatic arthritis; rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy). For the treatment of dermatomyositis, temporal arteritis, polymyositis, and systemic lupus erythematosus.

Source: the FDA label for Solu-Cortef (Pharmacia & Upjohn Company LLC), September 29, 2026. Full label on DailyMed 

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