Brand-name prescription

Spravato

esketamine

Compare your options

Compare	SpravatoBrand name	Authorized genericWithout the Spravato name	Regular genericesketamine
What pharmacies pay	$428per vial	Not sold	Not sold
Same as Spravato?	The original	–	–
Ways to save	Maker’s cardas little as $10 a treatmentwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: No generic is sold yet.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Johnson & Johnson (Janssen)

SPRAVATO withMe Savings Program

With commercial insurance

as little as $10 a treatment

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

Get it on jnjwithme.com

In the maker’s words

“Eligible patients pay $10 per treatment for SPRAVATO medicine costs…”

From the maker’s offer on jnjwithme.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Spravato’s own card may bring it to as little as $10 a treatment.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Spravato
56 mg dose packper vial	$428

Good to know

There’s no authorized generic of Spravato.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.