How do you pay?

How to pay the least

Ask for the cash price

Strensiq

Strensiq is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Strensiq’s cash price, and one or two other pharmacies too.
  2. Strensiq’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameStrensiq
Authorized genericasfotase alfa
Regular genericasfotase alfa
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Strensiq?
The original
–
–

Brand nameThe maker’s card

Alexion OneSource CoPay Program

Savings card from Alexion (AstraZeneca Rare Disease)

No insuranceNeeds insuranceNo cash price listed.
Insurance $0

Sign up on alexiononesource.com 

See the offer on alexiononesource.com

From the maker’s offer on alexiononesource.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Strensiq itself, from the same company, sold without the brand name, and usually for less. For now Strensiq is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Strensiq is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

STRENSIQ is a tissue nonspecific alkaline phosphatase indicated for the treatment of patients with perinatal/infantile- and juvenile-onset hypophosphatasia (HPP).

Source: the FDA label for Strensiq (Alexion Pharmaceuticals, Inc.), December 12, 2025. Full label on DailyMed 

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