Sulfatrim vs. generic sulfamethoxazole and trimethoprim: side by side

How to pay the least

Ask for the cash price

Generic sulfamethoxazole and trimethoprim

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic sulfamethoxazole and trimethoprim.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Sulfatrim, and the FDA requires it to work the same way.

Compare every option

Brand nameSulfatrim

Authorized genericsulfamethoxazole and trimethoprim

Regular genericsulfamethoxazole and trimethoprim

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Not soldThere isn’t one

Cash priceAsk the pharmacyUsually the lowest

Same as Sulfatrim?

The original

–

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Sulfatrim’s maker. Ask the pharmacy for Sulfatrim’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Sulfatrim itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWho makes it

5 companies sell a generic of Sulfatrim that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

ANI Pharmaceuticals200 mg/5 mL / 40 mg/5 mL

Has a dye: FD&C Red No. 40 · Made by Novitium Pharma

Product page on anipharmaceuticals.com

How it looks, what’s in it, NDCs

200 mg/5 mL / 40 mg/5 mL Pink

Package NDC
Bottle of 473 mL 70954-258-10

Inactive ingredients: cellulose, microcrystalline, carboxymethylcellulose sodium, sorbitol, methylparaben, sodium benzoate, anhydrous citric acid, glycerin, polysorbate 80, water, saccharin sodium monohydrate, silicon dioxide, FD&C Red No. 40, starch, corn, maltodextrin, dimethicone
FDA label
Aurobindo Pharma200 mg/5 mL / 40 mg/5 mL

Has a dye: FD&C Red No. 40

Product page on aurobindousa.com

How it looks, what’s in it, NDCs

200 mg/5 mL / 40 mg/5 mL Pink

Package NDC
Bottle of 50 mL 65862-496-50
Bottle of 100 mL 65862-496-01
Bottle of 473 mL 65862-496-47

Inactive ingredients: alcohol, carboxymethylcellulose sodium form, anhydrous citric acid, silicon dioxide, FD&C Red No. 40, glycerin, methylparaben, microcrystalline cellulose, polysorbate 80, water, saccharin sodium, sodium benzoate, sorbitol
FDA label
Chartwell RX200 mg/5 mL / 40 mg/5 mL, 800 mg/20 mL / 160 mg/20 mL

Has dyes: FD&C Red No. 40, FD&C Yellow No. 6

How it looks, what’s in it, NDCs

200 mg/5 mL / 40 mg/5 mL Opaque pinkish orange

Package NDC
Bottle of 473 mL 62135-749-47

800 mg/20 mL / 160 mg/20 mL Opaque pinkish orange

Package NDC
Box of 400 mL 62135-873-24

Inactive ingredients: alcohol, methylparaben, sodium benzoate, anhydrous citric acid, FD&C Red No. 40, FD&C Yellow No. 6, glycerin, microcrystalline cellulose, polysorbate 80, water, saccharin sodium, carboxymethylcellulose sodium, trisodium citrate dihydrate, sorbitol solution
FDA label
Kesin Pharma200 mg/5 mL / 40 mg/5 mL

Has a dye: FD&C Red No. 40 · Made by Prasco Laboratories

How it looks, what’s in it, NDCs

200 mg/5 mL / 40 mg/5 mL Syrupy

Package NDC
Carton of 800 mL 81033-012-40

Inactive ingredients: citric acid monohydrate, sodium benzoate, microcrystalline cellulose, methylparaben, carboxymethylcellulose sodium form, FD&C Red No. 40, saccharin sodium, glycerin, alcohol, polysorbate 80, water, sorbitol
FDA label
Prasco Laboratories200 mg/5 mL / 40 mg/5 mL

Has a dye: FD&C Red No. 40

How it looks, what’s in it, NDCs

200 mg/5 mL / 40 mg/5 mL Pink

Package NDC
Bottle of 473 mL 66993-727-57

Inactive ingredients: alcohol, methylparaben, sodium benzoate, carboxymethylcellulose sodium form, citric acid monohydrate, glycerin, microcrystalline cellulose, polysorbate 80, water, saccharin sodium, sorbitol, FD&C Red No. 40
FDA label

Package	NDC
Bottle of 473 mL	70954-258-10

Package	NDC
Bottle of 50 mL	65862-496-50
Bottle of 100 mL	65862-496-01
Bottle of 473 mL	65862-496-47

Package	NDC
Bottle of 473 mL	62135-749-47

Package	NDC
Box of 400 mL	62135-873-24

Package	NDC
Carton of 800 mL	81033-012-40

Package	NDC
Bottle of 473 mL	66993-727-57

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Sulfatrim, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

To reduce the development of drug-resistant bacteria and maintain the effectiveness of sulfamethoxazole and trimethoprim oral suspension and other antibacterial drugs, sulfamethoxazole and trimethoprim oral suspension should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.

Urinary Tract Infections

For the treatment of urinary tract infections due to susceptible strains of the following organisms: Escherichia coli, Klebsiella species, Enterobacter species, Morganella morganii, Proteus mirabilis and Proteus vulgaris. It is recommended that initial episodes of uncomplicated urinary tract infections be treated with a single effective antibacterial agent rather than the combination.

Acute Otitis Media

For the treatment of acute otitis media in pediatric patients due to susceptible strains of Streptococcus pneumoniae or Haemophilus influenzae when in the judgment of the physician sulfamethoxazole and trimethoprim offers some advantage over the use of other antimicrobial agents. To date, there are limited data on the safety of repeated use of sulfamethoxazole and trimethoprim in pediatric patients under two years of age. Sulfamethoxazole and trimethoprim is not indicated for prophylactic or prolonged administration in otitis media at any age.

Acute Exacerbations of Chronic Bronchitis in Adults

For the treatment of acute exacerbations of chronic bronchitis due to susceptible strains of Streptococcus pneumoniae or Haemophilus influenzae when in the judgment of the physician sulfamethoxazole and trimethoprim offers some advantage over the use of a single antimicrobial agent.

Shigellosis

For the treatment of enteritis caused by susceptible strains of Shigella flexneri and Shigella sonnei when antibacterial therapy is indicated.

Pneumocystis Carinii Pneumonia

For the treatment of documented Pneumocystis carinii pneumonia and for prophylaxis against Pneumocystis carinii pneumonia in individuals who are immunosuppressed and considered to be at an increased risk of developing Pneumocystis carinii pneumonia.

Travelers' Diarrhea in Adults

For the treatment of travelers' diarrhea due to susceptible strains of enterotoxigenic E. coli.

Source: the FDA label for Sulfatrim (PAI Holdings, LLC dba PAI Pharma), March 6, 2025. Full label on DailyMed

Good to know

A regular generic may look different from Sulfatrim. The FDA requires it to work the same way.
We didn’t find a savings card from Sulfatrim’s maker.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/sulfatrim/