Brand-name prescription

Sylvant

siltuximab

Compare your options

Sylvant is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

Compare	SylvantBrand name	Authorized genericWithout the Sylvant name	Regular genericsiltuximab
What pharmacies pay	Price not listed	Not sold	Not sold
Same as Sylvant?	The original	–	–
Ways to save	Maker’s cardas little as $0 an infusionwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: Sylvant is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Recordati Rare Diseases

SYLVANT Financial Assistance (RRD Patient Solutions)

With commercial insurance

as little as $0 an infusion

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

Get it on sylvant.com

In the maker’s words

“Eligible patients pay as little as $0 per infusion…”

From the maker’s offer on sylvant.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Good to know

There’s no authorized generic of Sylvant.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to the clinic’s billing office.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.