Symproic savings card: as little as $0 a prescription with commercial insurance

How to pay the least

Cash price

$480+ for 30 tablets

Pharmacies pay about this for Symproic; you’d pay more.

Ask your pharmacy for Symproic’s cash price, and one or two other pharmacies too.
Symproic’s savings card works only with insurance from a job or one you bought.

Has to be Symproic? With Optum Perks’ free coupon, Target (CVS) lists it for $545 for 30 tablets without insurance.

Get the free Optum Perks coupon

No generic is sold yet.

Compare every option

Brand nameSymproic

Authorized genericnaldemedine

Regular genericnaldemedine

What you’d pay

At least$480for 30 tablets; pharmacies pay this

Not soldThere isn’t one

Not soldNone sold yet

Same as Symproic?

The original

–

Brand nameThe maker’s card

SYMPROIC Savings Program

Savings card from BioDelivery Sciences International

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 a prescription

The card takes up to $150 a month off your co-pay.

Or call 1-855-408-8282.

In the maker’s words

“Commercially insured patients may pay as little as $0 for each prescription.”

From the maker’s offer on symproic.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Brand nameWith a free discount coupon

Optum Perks, Optum’s free discount coupon, lists these prices for Symproic without insurance. Show the coupon from its page at the pharmacy; it can’t be used with insurance.

From Optum Perks, read November 2, 2026, with no location set. Its page opens on this dose; other doses and pharmacies near you are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold

There isn’t one. An authorized generic is Symproic itself, from the same company, sold without the brand name, and usually for less. For now Symproic is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Constipation from opioid pain medicines

What the FDA label says

SYMPROIC is an opioid antagonist indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain, including patients with chronic pain related to prior cancer or its treatment who do not require frequent (e.g., weekly) opioid dosage escalation

Source: the FDA label for Symproic (BioDelivery Sciences International Inc), July 25, 2025. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/symproic/