How do you pay?

How to pay the least

Cash price

$4,580+ for 30 tablets

Pharmacies pay about this for Symtuza; you’d pay more.

  1. Ask your pharmacy for Symtuza’s cash price, and one or two other pharmacies too.
  2. Symtuza’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Johnson & Johnson Patient Assistance Program. Patients’ income must be equal to or less than 300% of Federal Poverty Level (FPL). Or call 1-833-742-0791.

See if you qualify 

No generic is sold yet.

Compare every option

Question
Brand nameSymtuza
Authorized genericdarunavir, cobicistat, emtricitabine, and tenofovir alafenamide
Regular genericdarunavir, cobicistat, emtricitabine, and tenofovir alafenamide
What you’d pay
At least$4,580for 30 tablets; pharmacies pay this
Not soldThere isn’t one
Not soldNone sold yet
Same as Symtuza?
The original
–
–

Brand nameThe maker’s card

J&J withMe Savings Program

Savings card from Johnson & Johnson (Janssen)

No insuranceNeeds insuranceNo cash price listed.
Insurance $0 a fill

The card takes up to $12,500 a year off your co-pay.

Sign up on jnjwithme.com 

Or call 1-833-742-0791.

In the maker’s words

“Eligible patients with commercial or private insurance pay $0 each time you fill your prescription.”

From the maker’s offer on jnjwithme.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Symtuza itself, from the same company, sold without the brand name, and usually for less. For now Symtuza is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

SYMTUZA is a four-drug combination of darunavir (DRV), a human immunodeficiency virus (HIV-1) protease inhibitor, cobicistat (COBI), a CYP3A inhibitor, and emtricitabine (FTC) and tenofovir alafenamide (TAF), both HIV-1 nucleoside analog reverse transcriptase inhibitors, and is indicated as a complete regimen for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 40 kg:

  • who have no prior antiretroviral treatment history or
  • who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen for at least 6 months and have no known substitutions associated with resistance to darunavir or tenofovir.

Source: the FDA label for Symtuza (Janssen Products LP), April 17, 2026. Full label on DailyMed 

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