How do you pay?

How to pay the least

Ask for the cash price

Tezspire

Tezspire is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Tezspire’s cash price, and one or two other pharmacies too.
  2. Tezspire’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Amgen Safety Net Foundation. Amgen Safety Net Foundation income requirements are based on a percentage of the Federal Poverty Level, adjusted for household size. Or call 1-800-932-3060.

See if you qualify 

Compare every option

Question
Brand nameTezspire
Authorized generictezepelumab-ekko
Regular generictezepelumab-ekko
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Tezspire?
The original
–
–

Brand nameThe maker’s card

TEZSPIRE Together Co-Pay Program

Savings card from Amgen / AstraZeneca

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a dose

Sign up on tezspire.com 

Or call 1-800-818-1770. See the offer on tezspire.com

In the maker’s words

“If you have commercial insurance, you may pay as little as $0 for each dose of medication with the TEZSPIRE Together Co-Pay Program.”

From the maker’s offer on tezspire.com, checked October 27, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Tezspire itself, from the same company, sold without the brand name, and usually for less. For now Tezspire is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Tezspire is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

TEZSPIRE is a thymic stromal lymphopoietin (TSLP) blocker, human monoclonal antibody (IgG2λ), indicated:

  • for the add-on maintenance treatment of adult and pediatric patients aged 12 years and older with severe asthma.
  • Limitations of Use:
  • Not for relief of acute bronchospasm or status asthmaticus.
  • for the add-on maintenance treatment of adult and pediatric patients aged 12 years and older with inadequately controlled chronic rhinosinusitis with nasal polyps (CRSwNP).

Source: the FDA label for Tezspire (Amgen Inc), October 17, 2025. Full label on DailyMed 

Good to know